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单项低水平抗—HBs阳性者对接种乙肝疫苗的免疫应答
引用本文:徐慧文,张建营.单项低水平抗—HBs阳性者对接种乙肝疫苗的免疫应答[J].解放军预防医学杂志,1991,9(4):268-273.
作者姓名:徐慧文  张建营
作者单位:西安医科大学流行病学教研室 西安 (徐慧文),西安医科大学流行病学教研室 西安(张建营)
摘    要:血清单项低水平抗-HBs阳性者,仅有15%的人对接种乙肝疫苗后出现了回忆反应。其余大部份人,抗-HBs持续时间及接种疫苗后的免疫反应与HBV标志全阴性组相比无显著差别;从低水平安慰剂组出现乙肝感染情况来看,可能仍是易感者。在制定接种乙肝疫苗方案时,应对这部份人足够重视。

关 键 词:乙肝疫苗  免疫应答  乙型肝炎  表面抗体

RESPONSE TO HEPATITIS B VACCINE IN SUBJECTS WITH LOW LEVELS OF ISOLATED ANTI-HBS
Xu Huiwne,Zhang Jianying Xi An Medical University,Xian.RESPONSE TO HEPATITIS B VACCINE IN SUBJECTS WITH LOW LEVELS OF ISOLATED ANTI-HBS[J].Journal of Preventive Medicine of Chinese People's Liberation Army,1991,9(4):268-273.
Authors:Xu Huiwne  Zhang Jianying Xi An Medical University  Xian
Abstract:The anamnestic response indicating past HBV infection was observed inonly 15 percent of subjects with isolated low levels anti-HBs when theywere vaccinated with hepatitis B vaccine. Most of the others may be regardedas susceptible persons on the basis that persistent length of anti-HBs andimmunologic response in these subjects with isolated low levels anti-HBsafter vaccination were not different from those of HBV seronegative group,and more over, HBV infection appeared in placebo group with isolated lowlevels anti-HBs. Therefore much attention must be payed to these subjectsin working out the scheme of hepatitis B vaccineation.
Keywords:Isolated low levels anti-HBs  Immunologic Response  Hepatitis B Vaccine    
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