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中西医结合治疗对肝豆状核变性患者P300的影响
引用本文:童建兵,王晓旸,高宁宾.中西医结合治疗对肝豆状核变性患者P300的影响[J].安徽中医学院学报,2007,26(6):14-15.
作者姓名:童建兵  王晓旸  高宁宾
作者单位:安徽中医学院第一附属医院神经内科,安徽,合肥,230031;安徽中医学院第一附属医院神经内科,安徽,合肥,230031;安徽中医学院第一附属医院神经内科,安徽,合肥,230031
摘    要:目的:观察肝豆状核变性(HLD)患者中西医结合治疗前后P300的变化.方法:对30例HLD患者采用中西医结合治疗,治疗前后行P300检测,并与健康对照组进行比较.结果:与健康对照组比较,HLD患者治疗前P300潜伏期(PL)延长(P<0.01),波幅(Amp)降低(P<0.01);治疗后P300 PL明显缩短(P<0.05),但Amp变化无统计学意义.结论:中西医结合疗法对HLD患者认知功能障碍具有较好疗效.

关 键 词:肝豆状核变性  中西医结合疗法
文章编号:1000-2219(2007)06-0014-02
修稿时间:2007年10月8日

Change of P300 in Hepatolenticular Degeneration Patients with Treatment Combining Traditional Chinese and Western Medicine
TONG Jian-bing,WANG Xiao-yan,GAO Ning-bin.Change of P300 in Hepatolenticular Degeneration Patients with Treatment Combining Traditional Chinese and Western Medicine[J].Journal of Anhui Traditional Chinese Medical College,2007,26(6):14-15.
Authors:TONG Jian-bing  WANG Xiao-yan  GAO Ning-bin
Abstract:Objective: To observe the change of P300 in hepatolenticular degeneration(HLD) patients with treatment combining traditional Chinese and western medicine.Methods: P300 of 30 HLD patients was analysed before and after one-month treatment by the HLD-Relief decoction supplemented with copper-clearing drug,and the result was compared with that of 30 patients in normal control group.Results:Compared with that of normal control group,the P300 latency was prolonged(P<0.01)and the P300 amplitude was lower(P<0.01)in HLD patients;after treatment,the P300 latency was shortened(P<0.05),but alteration of the P300 amplitude was not significantly different.Conclusion: Treatment combining traditional Chinese and western medicine produces a marked effect on cognitive dysfunction in HLD patients.
Keywords:Hepatolenticular degeneration  Treatment combining traditional Chinese and western medicine
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