71例药物不良反应报告分析

目的对肝病医院的药物不良反应（ADR）进行分析，促进临床安全合理地使用药物。方法收集本院肝病医院中2008年ADR报告71例，按照患者性别、年龄分布、药品种类及品种、给药途径、ADR临床表现等进行统计分析。结果71例ADR报告中，抗感染药物所致ADR居首位；所致ADR的药物大多为静脉注射；涉及系统以皮肤及其附件最为常见，经过相应的治疗均好转或治愈。结论重视ADR的监测工作和提高ADR的报告水平，以减少ADR发生。

Analysis of 71 adverse drug reaction reports

Objective To analyze the occurrences of adverse drug reaction （ADR） in liver disease hospital and to promote a rational clinical drug use. Methods 71 ADR reports collected in our liver disease hospital in 2008 were analyzed statistically in terms of sex and age distribution of patients, the drug varieties, administering methods and clinical manifestations. Results Of the total 71 ADR cases, most were induced by antibiotic drugs. Most were induced by injection in vein. The most common clinical manifestations were the damage of skin and its accessory. After the corresponding treatment, ADR of patients had improved or cured. Conclusions To decrease the incidence of ADR, the ADR monitoring work should be emphasized and report quality should be improved.