先天性肾上腺皮质增生所致女性假两性畸形的CT 诊断及临床表现

目的：探讨先天性肾上腺皮质增生所致女性假两性畸形的CT 表现特点及诊断价值。方法经手术及临床诊断为先天性肾上腺皮质增生所致女性假两性畸形6例患者,分析其CT 表现及特点。结果6例患者均未经激素治疗,双侧肾上腺内外肢弥漫性增粗、迂曲、延长,1例表现为结节状、串珠状增生;轮廓清晰,密度均匀,增强扫描呈明显、均匀、同步强化。结论肾上腺弥漫性、串珠状增生有一定的特征性,有助于提高女性假两性畸形的影像诊断敏感性,结合临床综合分析,做出正确诊断。

CT characteristics and their clinical value of female pseudohermaphroditism caused by congenital adrenal cortex hyperplasia

Objective To evaluate the CT characteristics and their clinical value of female pseudohermaphroditism caused by congenital adrenal cortex hyperplasia .Methods The CT manifestations and characteristics of 6 patients ,who suffered from female pseudohermaphroditism caused by congenital adrenal cortex hyperplasia confirmed by operation and clinic , were retrospectively analyzed .Results All 6 patients were not received any hormone therapy .Those cases presented with the diffuse thickening ,prolongation and twist of bilateral adrenal glands and 1 case presented with nodular or beaded hy‐perplasia .All cases exhibited clear outline and ,uniform density .The enhanced scanning showed obvious ,uniform ,aand synchronization enhancement .Conclusion The diffuse and beaded hyperplasia of adrenal glands has certain characteris‐tics ,which is helpful for improving the image diagnostic sensitivity of female pseudohermaphroditism .Ccombined with the clinical manifestations and laboratory examinations for the comprehensive analysis ,the right diagnosis can be made in clini‐cal practice .