| 硅橡胶及其共聚物包膜材料的血液相容性及透析性的实验研究 |
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| 引用本文： | 刘有初,董光皎,王修宇.硅橡胶及其共聚物包膜材料的血液相容性及透析性的实验研究[J].第四军医大学学报,1988(4). |
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| 作者姓名： | 刘有初 董光皎 王修宇 |
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| 作者单位： | 第四军医大学化学教研室
(刘有初，董光皎)，陕西机械学院物理学教研室(王修宇) |
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| 摘 要： | 体外实验表明,用~(60)Co辐射法制备的硅橡胶及其共聚物包膜炭,对利眠宁的吸附能力很强。共聚物的透析性比硅橡胶膜有所提高,经扫描电子显微镜和光栅位相假彩色编码观察,聚甲基乙烯基硅橡胶与甲基丙烯酸共聚物膜粘附血小板数为活性炭的8％,为聚甲基乙烯基硅橡胶的28％,血小板破坏和变形很小。聚甲基乙烯基硅橡胶与甲基丙烯酸共聚物是血液相容性与透析性良好的,有希望的吸附型人工肝肾包膜材料。
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| 关 键 词： | 辐射 硅橡胶共聚物 血液相容性 血液透析 假彩色化 |
An Approach to Hemocompatihility and Permeability of Activated Charcoal Coated with Silastic and Its Copolymers |
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| Liu Youchu,et al..An Approach to Hemocompatihility and Permeability of Activated Charcoal Coated with Silastic and Its Copolymers[J].Journal of the Fourth Military Medical University,1988(4). |
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| Authors: | Liu Youchu |
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| Institution: | Liu Youchu,et al. Department of Chemistry |
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| Abstract: | The results of our in vitro studies show that the permeability of silastic and its copolymer-coated charcoal for librium is very high. The detoxication efficacy of the coating appeared PMVS-MA-AC>PMVS-AM-AC>PMVS-AC. The platelets OH PMVS-MA copolymer were slightly deformed. The number of adhered platelets to the copolymer coating was 28% of the platelets adhered to PMVS and was only 8% of the platelets adhered to AC. The results suggest that the hemo-compatibility of the PMVS-MA copolymer induced by radiation is better than silastic and that the copolymer coatings are likely to be used hopefully for detoxication of artificial kidney or artificial liver. |
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| Keywords: | radiation silastic copolymer hemocompatibility hemodialysis pseudocoloring |
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