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PET/CT诊断恶性肿瘤及其转移灶的价值
引用本文:吴湖炳,王全师,王明芳,王欣璐,郭晓君. PET/CT诊断恶性肿瘤及其转移灶的价值[J]. 中华核医学杂志, 2005, 25(2): 84-86,i004
作者姓名:吴湖炳  王全师  王明芳  王欣璐  郭晓君
作者单位:510515,广州,第一军医大学附属南方医院PET中心
摘    要:目的探讨PET/CT对恶性肿瘤及其转移灶的检测效能。方法恶性肿瘤患者65例皆行PET/CT检查,原发灶皆经病理组织学确诊,转移灶的诊断综合组织病理学结果及多种影像学检查而定。行^18F-脱氧葡萄糖(FDG)PET/CT融合图像、唧图像和CT图像帧对帧对比分析。结果初诊恶性肿瘤患者59例,有恶性病灶264个。264个病灶中,唧与平扫CT阅片均有肯定诊断结论者128个,占48.4%;而唧有肯定诊断结论,但CT难以有肯定诊断结论者111个,占42.0%;唧显像为阴性或难以确定,而CT有肯定诊断结论者11例共25个病灶.占9.6%。PET/CT的总检出率高于PET和CT。6例治疗后患者,CT难以确定肿瘤残余和坏死区域,而PET/CT能清楚区分。结论PET/CT可提高对恶性肿瘤诊断及分期的准确性。

关 键 词:转移灶 CT诊断 ^18F-脱氧葡萄糖 PET/CT 恶性肿瘤患者 价值 CT融合图像 恶性肿瘤诊断 病理组织学 影像学检查 组织病理学 CT检查 对比分析 CT图像 平扫CT 总检出率 肿瘤残余 原发灶 病灶 治疗后 准确性

The clinical value of PET/CT imaging on diagnosis of malignancy and metastasis
WU Hu-bing,WANG Quan-shi,WANG Ming-fang,et al.. The clinical value of PET/CT imaging on diagnosis of malignancy and metastasis[J]. Chinese Journal of Nuclear Medicine, 2005, 25(2): 84-86,i004
Authors:WU Hu-bing  WANG Quan-shi  WANG Ming-fang  et al.
Affiliation:WU Hu-bing,WANG Quan-shi,WANG Ming-fang,et al. PET Center,Nanfang Hospital,The First Military Medicial University of PLA,Guangzhou 510515,China
Abstract:Objective To explore the clinical value of PET/CT imaging on the diagnosis of malignancy and metastasis. Methods 65 patinets with malignancy were studied. The primary lesions were all proved by pathology and the metastatic lesions were diagnosed by the pathology combined with other imaging modalities. PET/CT fusion images,PET images and CT images of the same patient were analyzed frame by frame. Results In 59 cases of initial diagnosis, 264 malignant lesions were detected. Among 264 lesions, 128 lesions (48.4%) were detected and dispalyed definitely by both PET and the plain scan of CT; 111 (42.0%) lesions were dectected definitely by PET but doubtful in the plain scan of CT; while 11 patients were negative by PET but definitely by the plain scan of CT. Hence, the sensitivity of PET/CT was more higher than PET and the plain scan of CT alone. In 6 cases after therapy, PET/CT could identify necrosis and residual tumor easily and clearly whereas the plain scan of CT could not. Conclusion PET/CT can increase the accuracy of the diagnosis and staging for malignancy.
Keywords:Neoplasms  Neoplasm metastasis  Tomography   emission-computed  Tomography   X-ray computed  Deoxyglucose
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