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Combined hamartomas of the retina and retinal pigment epithelium
Authors:A P Schachat  J A Shields  S L Fine  G E Sanborn  T A Weingeist  R E Valenzuela  A J Brucker
Affiliation:3. Department of Ophthalmology, University Hospitals, Iowa City;4. The Department of Ophthalmology, University of Mississippi Medical Center, Jackson;6. The Scheie Eye Institute, University of Pennsylvania, Philadelphia.
Abstract:Combined hamartomas of the retina and retinal pigment epithelium are rare fundus lesions. By combining cases seen by members of The Macula Society, clinical data was collected on 60 patients with combined hamartomas. We reviewed the clinical presentations, ophthalmoscopic, and fluorescein angiographic features and differential diagnosis of this tumor. Of 41 patients with adequate follow-up information, 10 (24%) lost at least two lines of visual acuity, usually due to tractional distortion of the fovea, and four (10%) had improved visual acuity following either amblyopia therapy or vitreous surgery for macular traction.
Keywords:amblyopia  choroidal neovascularization  combined hamartoma of the RPE and retina  epiretinal membrane  hamartoma  intraocular tumor  uveal melanoma  uveal pseudomelanoma
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