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Prolonged curarisation following renal transplantation
Authors:JANE M. ROUSE  R. L. A. GALLEY  D. R. BEVAN
Affiliation:Jane M. Rouse, MB, BS, Registrar, R.L.A. Galley, MB, BS, Registrar and D.R. Bevan, MB, BChir, MRCP, FFARCS, Senior Lecturer, Department of Anaesthetics, St Mary's Hospital, Praed Street, London W2 1NY. Correspondence should be addressed to Dr D.R. Bevan.
Abstract:A retrospective study of postoperative respiratory morbidity in 247 patients requiring renal transplantation between 1955 and 1973 showed that 7 patients required postoperative controlled ventilation for up to 6 days. The nondepolarising relaxants tubocurarine and pancuronium were used in only 65 patients, but all 7 cases of respiratory failure occurred in this group. This suggests that the use of these drugsin anephric patients is potentially hazardous so far as postoperative respiratory insufficiency is concerned.
Keywords:KIDNEY    transplantation    NEUROMUSCULAR RELAXANTS    tubocurarine    pancuronium    prolongation
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