超声双重造影对胃癌分化程度的初步评价

目的 探讨口服胃窗超声造影联合静脉超声造影(超声双重造影)对胃癌分化程度的评估价值.方法 53例经胃镜诊断为胃癌并经术后病理证实的患者在术前进行超声双重造影,按分化程度分为中高分化腺癌组(A组)及低分化癌组(B组),将造影结果与术后病理组织分化结果进行对照,分析病灶大小、增强特点与病理分化程度的关系.结果 超声造影下胃癌病灶大小、增强分布与病理分化程度密切相关,分化程度越低的肿瘤瘤体较大、增强倾向于不均匀;低分化癌组基础强度明显低于中高分化腺癌组[(0.52±1.12)dB对(1.53±1.87)dB,P<0.05],增强强度明显高于中高分化腺癌组[(26.22±3.69)dB对(23.69±5.02)dB,P<0.05].结论 超声双重造影可对术前胃癌的分化程度进行初步评价.

Pilot study of double contrast ultrasonography for differentiation degree of gastric cancer

Objective To investigate the value of oral and intravenous contrast enhanced ultrasonography-double contrast ultrasonography (DCUS) in the evaluation of differentiation degree of gastric cancer. Methods Fifty-three patients who had been diagnosed as gastric cancer by gastroscope and confirmed by pathology after operation were examined by DCUS, and they were divided into moderately to well differentiated group and poorly differentiated group. The correlation of size and enhancement features of the lesions was compared with differentiation degree of gastric cancer. Results The size and enhancement distribution of lesions were markedly correlated with the degree of differentiation. The baseline intensity(BI)in poorly differentiated group was lower than that in well and moderately differentiated group[(0.52±1.12)dB vs (1.53±1.87) dB, P<0.05], but enhanced intensity(EI) was higher than that in the second group [(26.22±3.69)dB vs (23.69±5.02)dB, P<0.05]. Conclusions DCUS could initial evaluate the degree of differentiation of gastric cancer before operation.