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正交试验优选镰形棘豆总黄酮活性炭脱色工艺
引用本文:杜青云,洪佳妮,李茂星,陈锦珊.正交试验优选镰形棘豆总黄酮活性炭脱色工艺[J].药学实践杂志,2011,29(2):105-108.
作者姓名:杜青云  洪佳妮  李茂星  陈锦珊
作者单位:1. 厦门大学医学院药学系,福建,厦门,361005;解放军第175医院药剂科,福建,漳州,363000
2. 兰州军区兰州总医院药材科,甘肃,兰州,730050
3. 解放军第175医院药剂科,福建,漳州,363000
基金项目:全军医药卫生"十一五"课题面上项目(06MB95);南京军区医药卫生科研课题 (06MA-95).
摘    要:目的优选镰形棘豆总黄酮活性炭脱色工艺。方法以温度、时间和活性炭用量为考察因素,脱色液颜色、260~420nm紫外吸收情况和总黄酮含量为考察指标,采用正交试验法探究最佳脱色条件。结果脱色最佳工艺为在40℃下,加入1%活性炭,搅拌5min。结论该脱色工艺可行,既能达到脱色效果,又能保留有效成分

关 键 词:镰形棘豆  总黄酮  脱色工艺  正交试验
收稿时间:2010/3/26 0:00:00
修稿时间:8/6/2010 12:00:00 AM

Optimization of decolorization technology of the Oxytropis falcata total flavones with active carbon by orthogonal experiment
DU Qing-yun,HONG Jia-ni,LI Mao-xing and CHEN Jin-shan.Optimization of decolorization technology of the Oxytropis falcata total flavones with active carbon by orthogonal experiment[J].The Journal of Pharmaceutical Practice,2011,29(2):105-108.
Authors:DU Qing-yun  HONG Jia-ni  LI Mao-xing and CHEN Jin-shan
Institution:Department of Pharmacy, Medical College of Xiamen University, Xiamen 361005,China;Department of Pharmacy, the 175th Hospital of PLA, Zhangzhou 363000,China;Department of Pharmacy, Medical College of Xiamen University, Xiamen 361005,China;Department of Pharmacy, the 175th Hospital of PLA, Zhangzhou 363000,China;Department of Pharmacy, Lanzhou General Hospital of PLA, Lanzhou 730050,China;Department of Pharmacy, the 175th Hospital of PLA, Zhangzhou 363000,China
Abstract:Objective To optimize the decolorization technology of Oxytropis falcata total flavones with active carbon.Methonds Temperature,stirring time and the content of active carbon were used as the orthogonal experiment factors.The colour of filtrate, the ultraviolet absorption between 260 nm to 420 nm and the content of total flavones were set as the indexes to investigate the optimal decolorization technology.Results The optimal decolorization technology was achieved under the condition as 40℃,stirring 5 min with 1%active carbon.Conclusion The decolorization technology is feasible which had good decolorization result and could hold effective ingredient
Keywords:Oxytropis falcata  total flavones  decolorization technology  orthogonal experiment
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