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扶正抑瘤方对晚期非小细胞肺癌化疗增效减毒作用及TSGF的影响
引用本文:张微微,陈越,张庆荃.扶正抑瘤方对晚期非小细胞肺癌化疗增效减毒作用及TSGF的影响[J].上海中医药杂志,2007,41(6):18-19.
作者姓名:张微微  陈越  张庆荃
作者单位:上海中医药大学附属岳阳中西医结合医院肿瘤科,上海,200437
摘    要:目的观察扶正抑瘤方对晚期非小细胞肺癌化疗毒副反应的减毒作用及其对肿瘤特异性生长因子(TSGF)水平的影响。方法将42例患者随机分为对照组(20例,采用单纯化疗治疗)和综合组(22例,化疗结合扶正抑瘤方治疗),21d为1个周期,两组均连续治疗2个周期。比较两组患者化疗通过率,毒副反应,生活质量,血清TSGF水平。结果综合组化疗通过率略高于化疗组,生活质量明显高于化疗组,化疗毒副反应小于化疗组,TSGF下降水平大于化疗组。结论自拟扶正抑瘤方能够改善晚期肺癌患者生活质量,能在一定程度上降低化疗的毒副反应,并协同化疗起到抑瘤的作用。

关 键 词:扶正抑瘤方  晚期非小细胞肺癌  肺瘤特异性生长因子  化疗
文章编号:1007-1334(2007)06-0018-02
修稿时间:2007-02-16

Effects of "Fuzheng Yiliu Decoction" on Chemotherapeutic Reactions and TSGF of Advanced Non-small Cell Lung Cancer
ZHANG Wei-wei,CHEN Yue,ZHANG Qing-quan.Effects of "Fuzheng Yiliu Decoction" on Chemotherapeutic Reactions and TSGF of Advanced Non-small Cell Lung Cancer[J].Shanghai Journal of Traditional Chinese Medicine,2007,41(6):18-19.
Authors:ZHANG Wei-wei  CHEN Yue  ZHANG Qing-quan
Abstract:To observe the clinical effects of "Fuzheng Yiliu Decoction" on non-small cell lung cancer and TSGF. Methods Forty-two subjects were randomized into two groups: control group in which 20 cases were treated simply by chemotherapy and treatment group in which 22 cases were treated with chemotherapy plus "Fuzheng Yiliu Decoction", with two courses. The chemotherapeutic effects, adverse reactions, quality of life and TSGF were observed. Results More patients in treatment group could endure chemotherapy; the quality of life was better, adverse reactions less and TSGF lower in treatment group than in control group. Conclusion "Fuzheng Yiliu Decoction" can improve the quality of life and relive adverse reactions in patients with advanced non-small cell lung cancer.
Keywords:"Fuzheng Yiliu Decoction"  non-small cell lung cancer  TSGF  chemotherapy
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