| 板蓝根化学成分研究（Ⅱ） |
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| 引用本文： | 丁水平,刘云海,李敬,秦国伟,吴晓云. 板蓝根化学成分研究（Ⅱ）[J]. 医药导报, 2001, 20(8): 475-476 |
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| 作者姓名： | 丁水平 刘云海 李敬 秦国伟 吴晓云 |
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| 作者单位： | 1. 华中科技大学同济医学院附属同济医院药学部
2. 中国科学院上海药物研究所 |
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| 基金项目： | 国家自然科学基金资助课题(NO:39870872),卫生部科学研究基金课题(NO:98-2-110) |
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| 摘 要： | 目的：提取分离板蓝根化学成分。方法：板蓝根用95％乙醇渗漉，用不同极性溶剂分级萃取，再分别用硅胶和大孔树脂做柱层析分离，测定纯化合物的理化常数和波谱数据，鉴定化学结构。结果：从板蓝根中分离得到31种化合物。结论：13种为已知化合物，18种为新发现，其中6种为新化合物，3种为首次从自然界中已分得的。其中的两种新化合物分别命名为isaindigotone,hydroxyindirubin。
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| 关 键 词： | 板蓝根 分离 提纯 化学成分 isaindigotone hydroxyindirubin |
| 文章编号： | 1004-0781(2001)08-0475-02 |
| 修稿时间： | 2001-04-03 |
Study of the Chemical Constituents of Isatis Indigotica Fort.( Cruciferea) |
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| DING Shui-ping,LIU Yun-hai,LI Jin,QIN Guo-wei,WU Xiao-yun. Study of the Chemical Constituents of Isatis Indigotica Fort.( Cruciferea)[J]. Herald of Medicine, 2001, 20(8): 475-476 |
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| Authors: | DING Shui-ping LIU Yun-hai LI Jin QIN Guo-wei WU Xiao-yun |
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| Affiliation: | DING Shui-ping1,LIU Yun-hai1,LI Jin1,QIN Guo-wei2,WU Xiao-yun2 |
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| Abstract: | Objective:To study the chemical constituents of Isatis indigotica fort.(cruciferae). Methods:The constituents were isolated on silica gel column chromatography,and identified by physico-chemical properties and structurally elucidated by spectral analysis (MS,H,CNMR,UV and IR). Results:31 compounds were obtained from the ethanol extracts of the rhizomes. Among them, three compounds were discovered for the first time from a natural source, eight compounds were originally isolated from this species and one from this plant. Six compounds were new chemiculs. Conclusion:The two compounds are new pigments,namely isaindigotone,hydroxyindirubin respectively. |
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| Keywords: | Isatisindigotica Fort.(Cruciferae) Isolation Purification New compounds |
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