| 3-芳基-6-三氯甲基-1,2,4-三唑并[3,4-b]-1,3,4-噻二唑的合成及其质谱研究 |
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| 引用本文： | 张海燕,张力学,张安将.3-芳基-6-三氯甲基-1,2,4-三唑并[3,4-b]-1,3,4-噻二唑的合成及其质谱研究[J].温州医学院学报,2003,33(5):295-297. |
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| 作者姓名： | 张海燕 张力学 张安将 |
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| 作者单位： | 1. 温州第十七中学,自然科学教研组,浙江,温州,325000
2. 温州师范学院,化学与材料科学学院,浙江,温州,325003 |
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| 基金项目： | 国家自然科学基金资助项目(29802004)，教育部高校骨干教师资助计划基金，浙江省自然科学资助项目。 |
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| 摘 要： | 目的：合成连有三氯甲基的稠杂环化合物，并研究其波谱(特别是质谱)的特征。方法：3-芳基-4-氨基-5-羟基-1，2，4-三唑与三氯乙酸在三氯氧磷存在条件下关环，合成了3-芳基-6-三氯甲基-1，2，4-三唑并3，4-b]-1，3，4-噻二唑。结果：这三个新化合物结构经元素分析、红外光谱、氢谱与质谱确证。结论：这些化合物质谱都有分子离子峰。当分子中有三个氯原子时，M 6：M 4：M 2：M=4：11：100：100。
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| 关 键 词： | 3-芳基-6-三氯甲基-1，2，4-三唑并[3，4-b]-1，3，4-噻二唑 合成 质谱 |
| 文章编号： | 1000-2138(2003)05-0295-03 |
| 修稿时间： | 2003年6月18日 |
Studies on the synthesis and mass spectra of 3-aryl-6-trichloromethyl - 1,2,4- triazolo[3,4-b]-1,3,4-thiadiazoles |
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| ZHANG Hai-yan,ZHANG Li-xue,ZHANG An-jiang. Natural Science Teaching and Research Group,Wewhou No. Middle School,Wenzhnu.Studies on the synthesis and mass spectra of 3-aryl-6-trichloromethyl - 1,2,4- triazolo[3,4-b]-1,3,4-thiadiazoles[J].Journal of Wenzhou Medical College,2003,33(5):295-297. |
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| Authors: | ZHANG Hai-yan ZHANG Li-xue ZHANG An-jiang Natural Science Teaching and Research Group Wewhou No Middle School Wenzhnu |
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| Institution: | ZHANG Hai-yan,ZHANG Li-xue,ZHANG An-jiang. Natural Science Teaching and Research Group,Wewhou No. 17 Middle School,Wenzhnu 325003 |
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| Abstract: | Objective:To synthesize some fused heterocycles containing trichloromethyl group and to study their mass spectral properties.Methods: Gave 3-aryl-6-trichloromethyl -1, 2, 4-triazolo3, 4-b]-l, 3, 4-thiadiazoles was synthesized during the cyclizarjon of 3-aryl-4-amino-5-meroapto-1 ,2,4-triazoles with trichloroacetic acid in the presence of phospho-rylchloride.Results:The structures of the three novel compounds were confirmed by elemental analysis.IR/H NMR and mass spectra.Conclusion:In the mass spectra,all the compounds have molecular ion peaks. M + 6: M+4: M+2: M is e-qual to 4:11:100; 100 when there are three chlorine atoms in a molecule. |
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| Keywords: | 3-aryl-6-trichloromethyl-l 2 4-triazolo[3 4-b]-l 3 4-thiadiazoles synthesis mass spectra |
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