原位肝移植64例术后ICU期间血乳酸及肝功能监测的临床意义

目的　探讨原位肝移植术后血乳酸和肝功能的动态变化的临床意义。方法　 64例原位肝移植患者术毕即转入重症监护病房 (ICU ) ,对全身重要脏器的功能和症状体征进行监测的同时观察血乳酸及肝功能动态变化值并分析相关因素。结果　原位肝移植术后患者血乳酸值正常或迅速下降至正常 ,患者肝功能恢复迅速预后良好 ,二者成正相关 (P <0 .0 1)。乳酸持续超过正常肝功能损害重预后不良。结论　动态血乳酸值是判断原位肝移植术后预后的良好指标。

The Monitoring and Signioficance of Blood Lactate Lever and Liver Function after Orthotopic Liver Transplantation During ICU of 64 Cases

Objective To study the clinical significance of blood lactate level and liver function after orthotopic liver transplantation (OLT) operation.Methods Between May 2002 and Feb 2003, 64 consecutive patients underwent OLT.After operation, the patients were send to intersive care unit (ICU) of hospital.The physiological function were determined,the symptopms and signs were observd, the blood lactate levere and liver function were measured befire,durung and after operation 1,12,36,60 hours,observed changes and amalysed relativity factors.Results In the 64 patients,the liver function came back favorable which the blood lactate levers were decreased rapidly to normal.They had positive correlation(P<0.01),contrarily,the liver function came back slowly or liver failure which the blood lactate levers were higher then normal.Conclusion To evaluate and montitring the blood lactate levels are excellent indicators of estimate OLT prognosis.