| 缺铁性贫血大鼠胸腺,脾脏的病理改变 |
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| 引用本文： | 张荷 廖清奎. 缺铁性贫血大鼠胸腺,脾脏的病理改变[J]. 临床血液学杂志, 1993, 6(3): 97-99 |
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| 作者姓名： | 张荷 廖清奎 |
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| 作者单位： | 华西医科大学附二院小儿血液/肿瘤研究室 610044(张荷，廖清奎，罗春华)，华西医科大学附二院小儿血液/肿瘤研究室 610044(张美瑜) |
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| 摘 要： | 通过光镜、电镜、酶组织化学染色(ANAE、ACP)对比观察了缺铁性贫血(IDA)大鼠和对照组大鼠胸腺、脾脏的病理改变。发现IDA大鼠胸腺有不同程度萎缩,胸腺和脾内淋巴细胞、ANAE、ACP阳性细胞减少;T淋巴细胞线粒体结构破坏。提示IDA时胸腺、脾内T淋巴细胞可能存在能量供应、细胞增殖及分化障碍。脾脏体积增大、充血,纤维组织增生。
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| 关 键 词： | 缺铁性贫血 大鼠 胸腺 脾脏 病理 |
The Pathologic Changes in Rat Thymus and Spleen Suffering from Iron Deficiency Anemia(IDA) |
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| Zhang He,Liao Qingkui,Luo Chunhua,et al Pediatric Hematology/Oncology Department in West China University of Medical Sciencises. The Pathologic Changes in Rat Thymus and Spleen Suffering from Iron Deficiency Anemia(IDA)[J]. Journal of Clinical Hematology, 1993, 6(3): 97-99 |
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| Authors: | Zhang He Liao Qingkui Luo Chunhua et al Pediatric Hematology/Oncology Department in West China University of Medical Sciencises |
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| Abstract: | The pathologic changes in rat(IDA group and control group) thy-mus and spleen were studied by the method of LM, EM, and ANAE/ACP stain. Thethymuses were smaller in IDA group than in control group. In the IDA group, thelymphocytes, and ANAE/ACP positive cells decreased and the structure of mitochon-dria in T-lymphocytes were broken. These findings prove that IDA may cause the en-ergy supplyment and multiplication and differenciation of the T-cell abnormal. We al-so found the spleen of IDA rats were enlarged and congested and the fibrous tissue inspleens was proliferated. |
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| Keywords: | IDA Rat Thymus Spleen T--lymphocyte |
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