国产可吸收钉治疗股骨头骨折的实验研究及临床评价

目的: 观察国产可吸收钉关节内植入后对周围组织的影响, 评价其在治疗股骨头骨折中的临床疗效。方法: 新西兰兔 6只于两侧膝关节内分别植入可吸收钉及金属钉; 4、8、12周后取标本, 行大体及组织学观察。临床 45例股骨头骨折患者采用国产可吸收钉固定。结果: 可吸收钉植入组, 仅表现组织对异物的正常反应; 金属钉组见关节软骨有明显的机械性损伤。45例患者, 随访 12~28个月, 优良率为 93%, 未发现不良反应。结论: 国产可吸收钉是治疗股骨头骨折理想的内固定物。

Experimental study and clinical evaluation of homemade absorbable screw in treatment of femoral head fracture

Objective:To observe the influence of homemade absorbable screw on tissues,and evaluate the effects of absorbable screw in treatment of femoral head fracture.Method:Six New Zealand rabbits were implanted absorbable and metal screw respectively in both knee joints.Specimen were obtained at the 4~ th,8~ th and 12~ th week,and observed macroscopically and microscopically.Forty-five patients of femoral head fracture were treated with homemade absorbable screw.Result:In absorbable screw group,only normal reactions to foreign body were found,and mechanical injuries to cartilage were clearly seen in metal group.In clinical group,45 patients with follow-up period of 12~28 months showed result of 93% good and satisfactory rate without complications.Conclusion:Homemade absorbable screw is the optimal internal fixation for femoral head fracture.