| 铅诱发人体染色体畸变的研究 |
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| 引用本文： | 王智芳,乔文建,宋劲修,李勇,云永玲,李桂玲,梁伶俐. 铅诱发人体染色体畸变的研究[J]. 华中科技大学学报(医学版), 1988, 0(4) |
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| 作者姓名： | 王智芳 乔文建 宋劲修 李勇 云永玲 李桂玲 梁伶俐 |
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| 作者单位： | 同济医科大学基础医学部生物学教研室(王智芳，云永玲)，同济医科大学基础医学部化学教研室(乔文建，李勇，李桂玲)，国营七五二厂职工医院(宋劲修)，国营七五二厂职工医院(梁伶俐) |
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| 摘 要： | 我们对32例接触铅的工人和20例对照组外周血淋巴细胞染色体畸变进行了研究。结果接触铅的工人与对照组相比,染色体畸变率、血铅、发铅、尿铅均有高度显著性差异(P<0.01),而且接触铅的工人的血铅、发铅、尿铅与染色体畸变率呈不同程度的正相关,其中以血铅与染色体畸变率相关最显著(γ=0.4219,P<0.01)。
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| 关 键 词： | 染色体畸变 铅 |
A Study of Chromosomal Aberration of Lymphocytes in Man Induced by Lead |
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| Wang Zhifang,Qiao Wenjian,Song Jingxiu,Li Yong,Yun Yongling,Li Gulling,Liang Lingli Faculty of Basic Medical Sciences,Tongji Medical University,Wuhan. A Study of Chromosomal Aberration of Lymphocytes in Man Induced by Lead[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1988, 0(4) |
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| Authors: | Wang Zhifang Qiao Wenjian Song Jingxiu Li Yong Yun Yongling Li Gulling Liang Lingli Faculty of Basic Medical Sciences Tongji Medical University Wuhan |
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| Abstract: | A Study of chromosomal aberration of lymphocytes was made in a group of 32 persons occupaticnally exposed to lead and in a control group of 20 persons. The results demonstrate that in the exposed group, the rate of chromosomal aberration, blood-lead level,hair-lead level and urine-lead level all had significantly higher than those in the control group (P<0.01). Furthermore, the blood-lead, hair-lead, urine-lead and the rate of chromosomal aberration of the exposed group showed positive correlation, among which the blood-lead level and the late of chromosomal aberration had even higher correlation in degree(r=0.4219,p<0.01). |
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| Keywords: | chromosome aberrations lead |
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