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The steroid hormone antagonist RU486. Mechanism at the cellular level and clinical applications. |
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| Authors: | E E Baulieu |
| Affiliation: | INSERM U 33 Lab Hormones, Bicêtre, France. |
| Abstract: | The cellular and molecular mechanism of RU486, a steroid hormone antagonist, is discussed in detail. Principally, RU486 opposes the action of two types of hormones: progesterone and glucocorticosteroids. The clinical applications are also described, as well as the future outlook. |
| Keywords: | |