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Annual decline in forced expiratory volume is steeper in aluminum potroom workers than in workers without exposure to potroom fumes
Authors:Vidar Søyseth MD  PhD  Paul K. Henneberger MPH  ScD  Gunnar Einvik MD  PhD  Mohammed Abbas Virji MSc  ScD  Berit Bakke MSc  PhD  Johny Kongerud MD  PhD
Affiliation:1. Medical Division, Akershus University Hospital, L?renskog, Norway;2. Faculty of Medicine, University of Oslo, Oslo, Norway;3. Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, West Virginia;4. Department of Occupational Health Surveilance, National Institute of Occupational Health, Oslo, Norway;5. Department of Respiratory Medicine, Rikshospitalet, Oslo University Hospital, Oslo, Norway
Abstract:

Background

Aluminum potroom exposure is associated with increased mortality of COPD but the association between potroom exposure and annual decline in lung function is unknown. We have measured lung volumes annually using spirometry from 1986 to 1996. The objective was to compare annual decline in forced expiratory volume in 1 s (dFEV1) and forced vital capacity (dFVC).

Methods

The number of aluminum potroom workers was 4,546 (81% males) and the number of workers in the reference group was 651 (76% males). The number of spirometries in the index group and the references were 24,060 and 2,243, respectively.

Results

After adjustment for confounders, the difference in dFEV1 and dFVC between the index and reference groups were 13.5 (P < 0.001) and ?8.0 (P = 0.060) ml/year.

Conclusion

Aluminum potroom operators have increased annual decline in FEV1 relative to a comparable group with non‐exposure to potroom fumes and gases. Am. J. Ind. Med. 59:322–329, 2016. © 2016 The Authors. American Journal of Industrial Medicine Published by Wiley Periodicals, Inc.
Keywords:lung function  longitudinal study  aluminum  smoking  potroom exposure  mixed model
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