炎症性肠病患者生存质量调查及影响因素分析

[目的]调查炎症性肠病患者的生存质量现况，分析影响生存质量的相关因素，为临床采取有效的干预措施提供依据。[方法]应用中文版SF-36量表，以自评法对92例炎症性肠病患者的生存质量进行调查，并与一般人群进行8个维度得分的比较。通过多元逐步回归分析，探讨影响生存质量的相关因素。[结果]炎症性肠病患者的SF-36总分波动在51．10-136．40范围。躯体角色、机体疼痛、总体健康、社会功能、情感角色5个维度的得分显著低于一般人群（P〈O．01）。回归分析发现，影响生存质量的因素主要有疾病活动指数、病情自评、年龄、工作（学习）状态、经济状况。[结论]炎症性肠病患者的生存质量低于一般人群。控制疾病活动指教，加强综合干预，可提高患者的生存质量。

A Survey of Quality of Life of Patients with Inflammatory Bowel Disease and Analysis of Affecting Factors

[Objective]To investigate the quality of life of patients with inflammatory bowel diseases and to analyze the factors affecting the quality of life so as to provide clinicians information on effective intervention measures. [Methods] Using SF-36 questionnaire, the quality of life of 92 patients with inflam- matory bowel diseases was surveyed and a comparison was made with general population. The affecting factors on quality of life were explored using multi- ple stepwise regression analysis. [Results]The SF-36 total scores in patients with inflammatory bowel disease ranged from 51.10 to 136.40. The scores on five dimensions of role physical, bodily pain, general health, social function, role emotional were significantly lower than the general population（P〈0.01）. Regression analysis showed that the factors affecting quality of life were mainly disease activity index, self evaluation on disease, age, working（studying） condition and economic situation. [Conclusions]Quality of life in patients with inflammatory bowel disease is lower than the general population. ControJ- ling disease activity index and strengthening comprehensive interventions can improve quality of life of the patients.