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Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors |
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| Authors: | Vera L Costa Rui Henrique Franclim R Ribeiro Mafalda Pinto Jorge Oliveira Francisco Lobo Manuel R Teixeira Carmen Jerónimo |
| Institution: | (1) Department of Genetics, Portuguese Oncology Institute, Porto, Portugal;(2) Department of Pathology, Portuguese Oncology Institute, Porto, Portugal;(3) Department of Urology, Portuguese Oncology Institute, Porto, Portugal;(4) Department of Pathology and Molecular Immunology, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, Porto, Portugal;(5) School of Health Sciences, Fernando Pessoa University, Porto, Portugal |
| Abstract: | BackgroundAberrant promoter hypermethylation of cancer-associated genes occurs frequently during carcinogenesis and may serve as a cancer biomarker. In this study we aimed at defining a quantitative gene promoter methylation panel that might identify the most prevalent types of renal cell tumors. |
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