| 哮喘患儿屋尘螨特异性免疫治疗的疗效及依从性分析 |
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| 引用本文： | 魏金凤,彭万胜,刘恩梅. 哮喘患儿屋尘螨特异性免疫治疗的疗效及依从性分析[J]. 中国新药与临床杂志, 2011, 0(5) |
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| 作者姓名： | 魏金凤 彭万胜 刘恩梅 |
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| 作者单位： | 浙江中医药大学附属第六医院;杭州市儿童医院呼吸科;重庆医科大学附属儿童医院呼吸中心; |
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| 摘 要： | 目的探讨儿童哮喘标准化尘螨特异性免疫治疗(SIT)的临床疗效及依从性。方法 67例进行标准化屋尘螨特异性免疫治疗的哮喘患儿,3年疗程结束后分为完成治疗SIT组(满3年组,42例)和未完成治疗SIT组(<3年组,25例),对哮喘患儿的临床症状、哮喘控制情况及依从性进行随访,并对结果进行统计学分析。结果满3年组与<3年组比较,其哮喘发作、急诊次数和输液日数均有显著改善(P<0.01);2组规范用药比较有显著差异(P<0.01);对SIT的效果,家属主观感觉,2组无显著差异,客观评价有显著差异(P<0.05),2组的主观评价无显著差异,但哮喘控制的客观评价存在显著差异(P<0.05);不完全依从的原因中,怀疑治疗效果和好转停药为最主要的原因,分别占32%和36%。结论 3年标准化屋尘螨特异性免疫治疗可显著改善哮喘患儿的临床症状,加强医、护、患沟通等措施对提高患者的依从性和哮喘的控制有积极的影响。
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| 关 键 词： | 儿童 哮喘 特异性免疫治疗 病人依从 |
Compliance and effect of specific immunotherapy for house dust mites in asthmatic children |
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| WEI Jin-feng,PENG Wan-sheng,LIU En-mei. Compliance and effect of specific immunotherapy for house dust mites in asthmatic children[J]. Chinese Journal of New Drugs and Clinical Remedies, 2011, 0(5) |
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| Authors: | WEI Jin-feng PENG Wan-sheng LIU En-mei |
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| Affiliation: | WEI Jin-feng~1,PENG Wan-sheng~2,LIU En-mei~2 (1.Department of Respiratory,the Sixth Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine/Hangzhou Children's Hospital,Hangzhou ZHEJIANG 310014,China,2.Department of Respiratory Diseases,Children's Hospital of Chongqing Medical University,CHONGQING 400014,China) |
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| Abstract: | AIM To evaluate the compliance and effect of specific immunotherapy(SIT) for house dust mites(HDM) in asthmatic children.METHODS A total of 67 patients with childhood asthma were treated with SIT with standardized extracts of HDM for 3 year.Forty-two patients finished the treatments were divided into SIT group and the other 25 patients were divided into unfinished SIT group.The curative effect and compliance in the two groups were compared after the treatment.RESULTS There were no significant differences in... |
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| Keywords: | child asthma specific immunotherapy patient compliance |
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