MR薄层定位扫描与常规扫描检测脑转移瘤数量的对比研究

目的评估脑转移瘤患者治疗前常规增强MR扫描和伽玛刀治疗所采用的薄层增强MR扫描检测脑转移瘤数量之间的不同。方法转移瘤的数量在治疗前和治疗中两次扫描图像上分别由2名医生确定,研究分析的两次MR图像间隔时间为4周以内。常规的增强MR扫描为层厚6 mm间隔2 mm,伽玛刀定位增强MR扫描是采取对刚性固定框架进行3.0 mm薄层无间隔扫描。结果 1336名患者中41.2%的患者在伽玛刀定位时发现转移瘤的数量增加,而数目相同者占58.8%,检测出从单发转移增加到多发转移占13.8%。在结直肠癌、食道癌病例中,单发转移的比例为66.2%,高于其他恶性肿瘤患者。结论大约有40%的患者在伽玛刀定位薄层图像扫描中发现转移瘤的数目增加,脑转移瘤患者的薄层MR增强扫描应当常规使用。

Thin-slice MR compared to conventional contrast-enhanced MR to determine number of brain metastases

Objective To evaluate differences in the numbers of brain metastases between thin-slice MR for gamma knife and conventional contrast-enhanced MR .Methods The numbers of metastases on the 2 images were counted by two doctors .Images from 1336 patients with an interval between the 2 MR studies of 4 weeks or less were analyzed .Conventional contrast-enhanced MR was 6 mm slice thickness and interval of 2 mm ,for gamma knife planning ,3 mm slice No interval scanning were taken under rigid frame fixation .Results Increases in the number of metastases were found in 41.2%of the 1336 patients,whereas the number was identical in 58.8%.An increase from single to multiple metastases was found in 13.8%.In cases with colorectal cancer and esophageal cancer ,the proportions of patients with a single metastasis 66.2% were higher than that of patients with other malignancies .Conclusions In about 40% of the patients , an increased number of metastases are found on the thin-slice images .Brain metastases from this to determine clinical treatment strategies have important significance .Therefore patients with brain metastases of thin-slice contrast-enhanced MR scanning should be used as convention .