| 正交试验优选强肝利胆口服液提取工艺 |
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| 引用本文： | 王军喜,孙文清,臧援朝,李晓玲,赵俊英.正交试验优选强肝利胆口服液提取工艺[J].中国药房,2005,16(18):1374-1376. |
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| 作者姓名： | 王军喜 孙文清 臧援朝 李晓玲 赵俊英 |
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| 作者单位： | 郑州市第六人民医院药剂科,郑州市,450052 |
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| 摘 要： | 目的:筛选强肝利胆口服液的最佳提取工艺。方法:采用正交设计试验,以总黄酮含量为指标,考察加水量、煎煮时间、煎煮次数、醇沉浓度4种因素对提取结果的影响。结果:最佳提取工艺为10倍药材量的水、煎煮时间60min、醇沉浓度50%、煎煮次数2次。结论:该工艺所制成品澄明度好,含量稳定。
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| 关 键 词： | 强肝利胆口服液 正交试验 总黄酮 制备工艺 |
| 文章编号： | 1001-0408（2005）18-1374-03 |
| 收稿时间： | 2004-11-16 |
| 修稿时间： | 2005-02-25 |
Optimization of Preparation Technics for Liver-strengthening Cholagogue Oral Preparations by Orthogonal Test |
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| WANG Junxi,SUN Wenqing,ZANG Yuanchao,LI Xiaolimg,ZHAO Junyin.Optimization of Preparation Technics for Liver-strengthening Cholagogue Oral Preparations by Orthogonal Test[J].China Pharmacy,2005,16(18):1374-1376. |
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| Authors: | WANG Junxi SUN Wenqing ZANG Yuanchao LI Xiaolimg ZHAO Junyin |
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| Abstract: | OBJECTIVE:To optimize the extraction technics of liver-strengthening cholagogue oral preparation.METHODS:The effects of the four factors-the quantity of the added water,the decoction time,the decoction times and the alcohol precipitation concentration on the extraction results were determined with content of total flavonoids taken as index.RESULTS:The best extracting condition was the following,the amount of the added water was 10 times that of the medicinal materials,the decoction duration was 60min,the alcohol precipitation concentration was 50%and the decoction was carried out twice.CONCLUSION:The preparation under this technics is of high clarity and stable contents. |
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| Keywords: | Liver-strengthening cholagogue oral preparation Orthogonal test Total flavonoids Preparation technics |
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