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不同经纬度肝癌临床特征年周期余弦曲线拟合参数对比
引用本文:Yu WX,Zuo MJ,Wang ZR,Huang HL,Xie ML,Zhang BC. 不同经纬度肝癌临床特征年周期余弦曲线拟合参数对比[J]. 中华肝脏病杂志, 2003, 11(6): 347-349
作者姓名:Yu WX  Zuo MJ  Wang ZR  Huang HL  Xie ML  Zhang BC
作者单位:1. 330006,南昌,江西医学院公共卫生学院
2. 江西医学院第二附属医院
3. 华西医科大学生物医学工程研究室
4. 江西省气象局
5. 江苏省启东市肝癌研究所
基金项目:国家自然科学基金(3936003,39860030)
摘    要:目的 根据爱因斯坦的“弯曲时空”理论及其场方程定律验证不同经纬度地区肝癌临床易表现 期是否具有同时性。方法 选择三个气候差异很大的不同经纬度地区采样,列出肝癌症状起始月份及临床检测 12个项目,共36个项目分别拟合成年周期余弦曲线(余弦法),对比峰值相位参数及调整中值与振幅的比值,来认 定是否为正比的同等范围。结果 三地区项目在年周期余弦曲线上峰值时相全部出现在-90.1°~-207.5°(4~7 月份),位于年周期的1/3同等范围。三地区中早期影像及谷胺酰转肽酶6个项目峰值相位全部出现在-98.5°~ -148.2°(4~5月份)。13个项目呈现明显节律特征。结论 三个地区肝癌恶性生长存在同一年生物周期模 式,4~7月份为肝癌临床易表现期(中早期在4~5月份),不同气候地区在该期间加强临床检测均可提高 中早期肝癌发现率。

关 键 词:  肝细胞  弯曲时空  不同经纬度  时间生物学  临床特征
修稿时间:2002-09-10

Comparison of the yearly cycle cosine curve imitative parameters of the clinical features of liver cancer at different longitude and latitude
Yu Wan-xian,Zuo Min-jing,Wang Zheng-rong,Huang He-lang,Xie Meng-li,Zhang Bao-chu. Comparison of the yearly cycle cosine curve imitative parameters of the clinical features of liver cancer at different longitude and latitude[J]. Chinese journal of hepatology, 2003, 11(6): 347-349
Authors:Yu Wan-xian  Zuo Min-jing  Wang Zheng-rong  Huang He-lang  Xie Meng-li  Zhang Bao-chu
Affiliation:Public Health School, Jiangxi Medical College, Nanchang 330006, China.
Abstract:OBJECTIVE: To explore whether there exists coincidence of the most appearing time of clinical features of liver cancer at different longitude and latitude, according to the law of field equation and the theory of warpage of space time by Einstein. METHODS: Three regions with different longitude and latitude were selected randomly and sampled. There were 36 items altogether, including 12 clinical items, which were used to imitate the yearly cycle cosine curve. The acorphases and the ratioes of amplitudes and means were compared to justifying whether they were in the same range. RESULTS: All the acorphases of 36 items appeared between -90.1degrees to -207.5 degrees (from april to july), existing in one third of the same range, in which 13 items occurred rhythmly (P<0.05). The image acorphases of liver cancer at the early and middle stage and gamma-glutamyl transpeptidase acorphase appeared between -98.5 degrees to -148.2 degrees (from april to may), in which 5 items occurred rhythmly (P<0.05). CONCLUSION: It is the same mode of the yearly biologcal cycle for liver cancer malignant growth within the most appearing time (from april to july). It will increase the detecting rate of liver cancer at the early and middle stage during this time (especially from april to may).
Keywords:Carcinoma   hepatocellular  Warpage of space time  Different longitude and latitude  Chronobiology  Clinical features
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