慢性肾衰竭急剧加重危险因素分析

目的　探讨慢性肾衰竭急剧加重因素及临床特点。方法　对 86例患者的病因、年龄、基础肾脏病及相关药物等进行分析。结果　在导致慢性肾衰竭急剧加重的因素中 ,老年组以肾毒性药物 ,严重感染等为主要原因 ,青壮年组以恶性高血压 ,原发病活动及急性左心衰等常见。 86例中 1 7例患者因原发病活动而导致慢性肾衰竭急剧加重 ,1 0例患者与药物相关。结论　慢性肾衰竭急剧加重的因素多种多样。老年者要警惕严重感染 ,药物性肾损害 ,青壮年患者积极控制高血压 ,原发病的活动及急性左心衰 ,对于预防慢性肾衰竭急剧加重具有十分重要意义。

Analysis of Aggravative Factor of Chronic Renal Failure

Objective To explore the deteriorative factors and clinical feature of chronic renal failure. Methods The etiology, age, basic renal diseases and correlative drugs of 86 patents with chronic renal failure were analyzed. Results Among the aggravative factors of chronic renal failure, the main factors were drugs with renal toxicity and severe infection in old-age patients, and they were malignant hypertension, activity of primary disease and acute left heart failure in young patients. Among 86 cases, 17 patients' condition were aggravated by activity of basic disease and 10 patients' aggravations were relative to drugs. Conclusions The acute deteriorating factors of chronic renal failure were multiplex. Severe infection and drugs with renal disease must be aware of in old-age patients, and young patients must control hypertension, activity of basic disease and acute left heart failure actively.