| 2种黔产淫羊藿总黄酮对免疫功能影响的比较研究 |
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| 引用本文： | 邓炜,郑民强,张静,黄聪,张雅莉. 2种黔产淫羊藿总黄酮对免疫功能影响的比较研究[J]. 中国中药杂志, 2011, 36(4): 511-513 |
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| 作者姓名： | 邓炜 郑民强 张静 黄聪 张雅莉 |
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| 作者单位： | 1. 贵阳中医学院药理教研室,贵州贵阳,550002
2. 贵阳中医学院第一附属医院,贵州贵阳,550001 |
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| 摘 要： | 目的:比较2种黔产淫羊藿总黄酮(TFE)对CTX小鼠免疫功能的影响.方法:采用CTX造免疫低下小鼠模型,同时给药10d,以体重、脾重、脾指数,血清溶血素浓度,血清TNF-α及IL-2含量为指标,观察2种TFE增强免疫作用,并比较其差异.结果:单次ip CTX 80m9·kg(-1),使正常小鼠的脾指数、血清溶血素水平、IL-2和TNF-α含量明显下降;ig 2种TFE1.3,0.65g·kg(-1)10d,可使体重、脾重、睥指数上升(P<0.01),下降的溶血素值回升(P<0.01),以及下降的IL-2和TNF-α含量显著升高(P<0.01).结论:2种黔产淫羊藿TFE对CTX小鼠的非特异免疫和特异免疫功能都具有明显增强作用;但2种黔产淫羊藿茎叶TFE增强免疫作用差异不明显.提示TFE中除了淫羊藿苷(ICA)外,尚有其他增强免疫的有效成分.
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| 关 键 词： | 黔岭淫羊藿 粗毛淫羊藿 淫羊藿总黄酮 增强免疫 比较研究 |
| 收稿时间： | 2010-10-13 |
Immunologic functions of total flavone of Epimedium of two species in Guizhou |
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| DENG Wei,ZHENG Minqiang,ZHANG Jing,HUANG Cong and ZHANG Yali. Immunologic functions of total flavone of Epimedium of two species in Guizhou[J]. China Journal of Chinese Materia Medica, 2011, 36(4): 511-513 |
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| Authors: | DENG Wei ZHENG Minqiang ZHANG Jing HUANG Cong ZHANG Yali |
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| Affiliation: | Department of Pharmacology, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China;Department of Pharmacology, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China;Department of Pharmacology, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China;Department of Pharmacology, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China;Radioimmunoassay Room of First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine, Guiyang 550001, China |
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| Abstract: | |
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| Keywords: | Epimedium leptorrhizum Epimedium acuminatum total flavones of Epimedium immunologic functions |
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