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复方普鲁卡因溶液对实验性胃溃疡的保护作用
引用本文:仲跻明,王有森,宋益民. 复方普鲁卡因溶液对实验性胃溃疡的保护作用[J]. 潍坊医学院学报, 2004, 26(1): 42-43
作者姓名:仲跻明  王有森  宋益民
作者单位:1. 潍坊医学院附属潍坊市人民医院,山东,潍坊,261041
2. 潍坊医学院
摘    要:目的观察复方普鲁卡因溶液对实验性胃溃疡的保护作用。方法以大鼠为实验对象,应用酸化乙醇诱导建立大鼠胃溃疡模型,以生理盐水为对照,用溃疡指数和溃疡抑制百分率进行评价。结果与生理盐水组比较,复方普鲁卡因溶液可明显降低大鼠溃疡指数,并且在本实验所用剂量范围内溃疡抑制率与剂量有关。结论复方普鲁卡因溶液对酸化乙醇诱导的大鼠胃溃疡具有明显的保护作用。

关 键 词:复方普鲁卡因溶液 胃溃疡 抗溃疡作用
文章编号:1004-3101(2004)01-0042-02
修稿时间:2003-08-17

Protective Effects of Composite Procaine Mixture on Experimental Gastric Ulcer
ZHONG Ji-ming ,WANG You-sen ,SONG Yi-min. Protective Effects of Composite Procaine Mixture on Experimental Gastric Ulcer[J]. Journal of Weifang Medical College, 2004, 26(1): 42-43
Authors:ZHONG Ji-ming   WANG You-sen   SONG Yi-min
Affiliation:ZHONG Ji-ming 1,WANG You-sen 1,SONG Yi-min 2
Abstract:Objective Study the protective effects of Composite procaine mixture on experimental gastric ulcer.Methods Set up acidulated alcohol induced ulcer models in rat.Useing physiological saline as control,the test was performed with three doses of Composite procaine mixture.The ulcer index was measured and the inhibitory rates were counted.Results Composite procaine mixture can reduce the ulcer index significantly(P<0.05,P<0.01).The inhibitory rates correlated with the doses in the area of the doses of the test.Conclusion Composite procaine mixture has protective effects on acidulated alcohol induced gastric ulcer in rat.
Keywords:Composite procaine mixture  Gastric ulcer  Against gastric ulceration
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