| IM患儿T淋巴细胞亚群及红细胞免疫功能的研究 |
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| 引用本文： | 王洪青,王延田,宋士洪. IM患儿T淋巴细胞亚群及红细胞免疫功能的研究[J]. 实用全科医学, 2010, 8(10): 1309-1310 |
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| 作者姓名： | 王洪青 王延田 宋士洪 |
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| 作者单位： | 王洪青,宋士洪,WANG Hong-qing,SONG Shi-hong(山东滕州市中心人民医院检验科,277500);王延田,WANG Yan-tian(山东枣庄市疾病预防控制中心,277100) |
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| 摘 要： | 目的探讨传染性单核细胞增多症患者（IM）机体T淋巴细胞亚群及红细胞免疫功能与病变的关系。方法在不同时相点（IM发病期,恢复期）用流式细胞仪检测患者外周血T淋巴细胞CD3＋,CD4＋,CD8＋,CD4＋/CD8＋,用免疫黏附法检测红细胞免疫黏附功能。结果与正常对照相比较,发病期患者CD3＋,CD4＋,CD8＋,CD4＋/CD8＋,红细胞免疫黏附功能明显异常降低,CD8＋明显增高（P〈0.01）。恢复期患者趋于正常。结论外周血T淋巴细胞亚群细胞及红细胞免疫黏附功能是IM患者免疫状态,评估预后的重要指标。
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| 关 键 词： | 传染性单核细胞增多症 T淋巴细胞亚群 红细胞免疫黏附 |
Immune Function of T-Lymphocyte Subgroup and Erythrocyte in Patient with Infectious Mononucleosis |
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| WANG Hong-qing,WANG Yan-tian,SONG Shi-hong. Immune Function of T-Lymphocyte Subgroup and Erythrocyte in Patient with Infectious Mononucleosis[J]. Applied Journal Of General Practice, 2010, 8(10): 1309-1310 |
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| Authors: | WANG Hong-qing WANG Yan-tian SONG Shi-hong |
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| Affiliation: | .Department of Medical Laboratory,Tengzhou Central Hospital,Tengzhou 277500,Shandong,China |
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| Abstract: | Objective To investigate the cellular immune function of T-Lymphocyte subgroup and erythrocyte in patient with infectious mononucleosis（IM）.Methods The peripheral blood CD3＋,CD4＋,CD8＋,CD4＋/CD8＋ were measured by flow cytometry at different time point of attack and restoration stage;and the erythrocyte immune function were measured by immune adhesion.Results The peripheral blood CD3＋,CD4＋,CD8＋,CD4＋/CD8＋ and erythrocyte immune adhesion function decreased,but CD8＋ increased in the treatment group as compared with the control group.The above index approximated to normal value as the status was improved.Conclusion The levels of T-Lymphocyte subgroup and erythrocyte immune function may be regarded as an index that reflects the state of immunity and prognosis of patients with IM. |
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| Keywords: | Infections mononucleosis T-Lymphocyte Subgroup Erythrocyte immune adhesion |
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