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Eosinophils and eosinophil-associated diseases: An update

Authors:	Jeremy A O&#x;Sullivan Bruce S Bochner

Institution:	Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill

Abstract:

Keywords:	Eosinophilopoiesis granule biogenesis eosinophil subsets apoptosis adipose tissue immunoregulation asthma chronic rhinosinusitis with nasal polyposis biologicals eosinophilic gastrointestinal disorder AAM Alternatively activated macrophage AT Adipose tissue BP Bullous pemphigoid COPD Chronic obstructive pulmonary disease CRS Chronic rhinosinusitis CRSwNP Chronic rhinosinusitis with nasal polyposis CRTH2 EGID Eosinophilic gastrointestinal disorder EGPA Eosinophilic granulomatosis with polyangiitis EoE Eosinophilic esophagitis EoP Eosinophil lineage–committed progenitor EPX Eosinophil peroxidase GMP Granulocyte-macrophage progenitor HES Hypereosinophilic syndrome IκBα NF-κB inhibitor α iEos Inflammatory eosinophils ILC2 Type 2 innate lymphoid cell MBP Major basic protein NF-κB Nuclear factor of κ light polypeptide gene enhancer in B cells PDGFRA Platelet-derived growth factor receptor α PIR-B Paired immunoglobulin-like receptor B PPI Proton pump inhibitor PPI-REE PPI-responsive esophageal eosinophilia Pre-GM Pre–granulocyte-macrophage progenitor PVAT Perivascular adipose tissue rEos Resident eosinophils Siglec Sialic acid–binding immunoglobulin-like lectin TH Tyrosine hydroxylase WT Wild-type XBP1 X-box binding protein 1
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