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Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung |
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| Authors: | Stéphane Mouraux Eric Bernasconi Céline Pattaroni Angela Koutsokera John-David Aubert Johanna Claustre Christophe Pison Pierre-Joseph Royer Antoine Magnan Romain Kessler Christian Benden Paola M. Soccal Benjamin J. Marsland Laurent P. Nicod |
| Affiliation: | 1. Service de Pneumologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland;2. Clinique Universitaire de Pneumologie, Pôle Thorax et Vaisseaux, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France;3. Université Grenoble Alpes, Grenoble, France;4. Institut National de la Santé et de la Recherche Médicale 1055, Saint Martin d''Hèes, France;5. L''institut du Thorax, Service de Pneumologie, Centre Hospitalier Universitaire de Nantes, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Université de Nantes, Nantes, France;6. Service de Pneumologie, Nouvel Hôpital Civil, Centre Hospitalier Universitaire, Strasbourg, France;g. Division of Pulmonology, University Hospital Zurich, Zurich, Switzerland;h. Division of Pulmonary Medicine, Geneva University Hospitals, Geneva, Switzerland |
| Abstract: |  |
| Keywords: | Airway remodeling fibroblasts macrophages matrix microbiota BAL Bronchoalveolar lavage CFU Colony-forming unit CHI3L1 Chitinase 3-like 1 CLAD Chronic lung allograft dysfunction COPD Chronic obstructive pulmonary disease GO Gene Ontology IGF Insulin-like growth factor IQR Interquartile range KEGG Kyoto Encyclopedia of Genes and Genomes KO KEGG ortholog MMP Matrix metallopeptidase PDGFD Platelet-derived growth factor D rRNA Ribosomal RNA SPP1 Secreted phosphoprotein 1 SysCLAD System prediction of Chronic Lung Allograft Dysfunction THBS1 Thrombospondin 1 THP-DM THP1-derived macrophages |
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