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A distinct biomolecular profile identifies monoclonal mast cell disorders in patients with idiopathic anaphylaxis |
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| Authors: | Melody C. Carter Avanti Desai Hirsh D. Komarow Yun Bai Sarah T. Clayton Alicia S. Clark Karina N. Ruiz-Esteves Lauren M. Long Daly Cantave Todd M. Wilson Linda M. Scott Olga Simakova Mi-Yeon Jung Jamie Hahn Irina Maric Dean D. Metcalfe |
| Affiliation: | 1. Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md;2. Hematology Section, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Md;3. Department of Nursing, Clinical Center, National Institutes of Health, Bethesda, Md;4. Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Md |
| Abstract: | |
| Keywords: | Anaphylaxis mast cells mastocytosis monoclonal mast cell activation syndrome mast cell activation tryptase KIT allele-specific quantitative PCR ASqPCR Allele-specific quantitative PCR bST Baseline serum tryptase gDNA Genomic DNA HV Healthy volunteer IA Idiopathic anaphylaxis ISM Indolent systemic mastocytosis MMAS Monoclonal mast cell activation syndrome NIH National Institutes of Health qPCR Quantitative PCR REMA Spanish Network on Mastocytosis SM Systemic mastocytosis |
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