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Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects |
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| Authors: | Natalie Garzorz-Stark Felix Lauffer Linda Krause Jenny Thomas Anne Atenhan Regina Franz Sophie Roenneberg Alexander Boehner Manja Jargosch Richa Batra Nikola S. Mueller Stefan Haak Christina Groß Olaf Groß Claudia Traidl-Hoffmann Fabian J. Theis Carsten B. Schmidt-Weber Tilo Biedermann Kilian Eyerich |
| Affiliation: | 1. Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany;2. Institute of Computational Biology, Helmholtz Center Munich, Member of the German Center for Lung Research (DZL), Neuherberg, Germany;3. ZAUM–Center of Allergy and Environment, Technical University and Helmholtz Center Munich, Member of the German Center for Lung Research (DZL), Munich, Germany;4. Institute for Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Munich, Germany;5. Institute of Environmental Medicine UNIKAT, Technical University and Helmholtz Center Munich, Augsburg, Germany;6. Department of Mathematics, Technical University of Munich, Garching, Germany |
| Abstract: |  |
| Keywords: | Psoriasis contact dermatitis imiquimod Aldara plasmacytoid dendritic cell IL-23 cytotoxicity Toll-like receptor innate immunity ACD Allergic contact dermatitis APC Allophycocyanin BDCA2 Blood dendritic cell antigen 2 HRP Horseradish peroxidase ICD Imiquimod-induced contact dermatitis NOS2 Nitric oxide synthase 2 pDC Plasmacytoid dendritic cell RT Room temperature TLR Toll-like receptor |
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