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Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis
Authors:Calum T. Robb  Henry J. McSorley  Jinju Lee  Tomohiro Aoki  Cunjing Yu  Siobhan Crittenden  Anne Astier  Jennifer M. Felton  Nicholas Parkinson  Adane Ayele  Richard M. Breyer  Stephen M. Anderton  Shuh Narumiya  Adriano G. Rossi  Sarah E. Howie  Emma Guttman-Yassky  Richard B. Weller  Chengcan Yao
Affiliation:1. Medical Research Council (MRC) Centre for Inflammation Research, Queen''s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom;2. Center for Innovation in Immunoregulative Technology and Therapeutics (AK Project), Kyoto University Graduate School of Medicine, Kyoto, Japan;3. Core Research for Evolutional Science and Technology, Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan;4. Department of Dermatovenereology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia;5. Department of Veterans Affairs, Tennessee Valley Health Authority, Nashville, Tenn;6. Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn;g. Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY;h. Laboratory for Investigative Dermatology, Rockefeller University, New York, NY
Abstract:
Keywords:Allergic contact dermatitis  atopic dermatitis  IL-22  ACD  Allergic contact dermatitis  AD  Atopic dermatitis  AHR  Aryl hydrocarbon receptor  cAMP  Cyclic AMP  db-cAMP  Dibutyryl cAMP  DC  Dendritic cell  EP  E prostanoid receptor  EtOH  Ethyl alcohol  Glyceraldehyde-3-phosphate dehydrogenase  ILC3  Group 3 innate lymphoid cell  LN  Lymph node  PG  Prostaglandin  PKA  Protein kinase A
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