| 2型糖尿病与恶性肿瘤 |
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| 引用本文： | 薛莹,刘超.2型糖尿病与恶性肿瘤[J].国际内分泌代谢杂志,2007,27(1):56-58,69. |
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| 作者姓名： | 薛莹 刘超 |
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| 作者单位： | 210029,南京医科大学第一附属医院内分泌科 |
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| 摘 要： | 2型糖尿病不仅是一个严重的健康问题，还与恶性肿瘤有着密切的联系。近年来流行病学研究证实2型糖尿病与一些常见恶性肿瘤如结、直肠癌、肝癌、胰腺癌、乳腺癌以及子宫内膜癌的发病有关，但其关联的确切机理仍无定论，可能与高血糖、胰岛素及胰岛素样生长因子、内皮素、脂联素、微量元素、激素和药物等诸多因素有关。
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| 关 键 词： | 2型糖尿病 恶性肿瘤 高血糖 胰岛素 胰岛素样生长因子 |
| 修稿时间： | 2006-06-19 |
The relation of type 2 diabetes mellitus and malignancy |
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| XUE Ying,LIU Chao.The relation of type 2 diabetes mellitus and malignancy[J].International JOurnal of Endocrinology and Metabolism,2007,27(1):56-58,69. |
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| Authors: | XUE Ying LIU Chao |
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| Institution: | Department of Endocrinology , The First Affiliated Hospital of Nanjing Medical University , Nanjing 210029, China |
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| Abstract: | Type 2 diabetes mellitus is a major public health issue, which is positively associated with risks of several common human malignancies. Increasing evidence indicates that individuals with type 2 diabetes mellitus are at elevated risk for several common human malignancies, including cancers of the colon, liver, pancreas, breast, and endometrium . Although there is no consensus on the mechanism, several factors are well accepted such as hyperglycemia, insulin, insulin-like growth factor, endothelin, trace element, hormone, medicine and so on. |
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| Keywords: | Type 2 diabetes mellitus Malignancy Hyperglycemia Insulin Insulin-like growth factor |
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