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益肾宝治疗慢性肾炎100例
引用本文:傅秀兰.益肾宝治疗慢性肾炎100例[J].中国新药与临床杂志,1994(6).
作者姓名:傅秀兰
作者单位:上海第二医科大学附属瑞金医院肾脏科
摘    要:慢性肾炎100例(男性54例,女性46例;年龄36±s12a)其中普通型50例、肾病型27例及高血压型23例;病程3.2±1.6a。采用益肾宝胶囊4粒,po,tid×30d治疗。结果:临床症状及周身水肿等均有显著好转。普通型及肾病型24h尿蛋白(包括系列微量蛋白)均显著降低,血清血红蛋白、白蛋白均显著升高(P<0.05或0.01)。肌酐清除率的升高及血清肌酐的降低仅普通型有显著意义(P<0.01或0.05)。而高血压型疗效不显著。总有效率普通型、肾病型及高血压型依次为90%,82%及70%。益肾宝无明显毒副作用。

关 键 词:益肾宝  中草药  肾炎  蛋白尿

Yi-shen-bao in treating chronic nephritis in 100 patients
FU Xiu-Lam.Yi-shen-bao in treating chronic nephritis in 100 patients[J].Chinese Journal of New Drugs and Clinical Remedies,1994(6).
Authors:FU Xiu-Lam
Abstract:One hundred chronic nephritis patients(M54, F46;age 36±s 12 a,common type n=50, nephrotic type n=27, hypertensive type n=23) were treated with Yi-shen-bao 4cap, po, tid, ×30 d.Results showed that all the clinical symptoms and general edema were significantly improved. For common type and nephrotic type, the quantitation of proteinuria in 24 h was significantly decreased(P<0.01),the level of hemoglobulin and serum albumin were all significantly increased(P<0.05).The urinary series microproteins (including Alb, IgG,Tf)were significantly decreased(P<0.05 or P<0.01). For common type,the clearance of creatinine was elevated and the value of serum creatinine was decreased, both of them had significant statistic diffference(P<0.01). In the hypertensive type all the laboratorv tests mentioned above had no statistic difference(P>0.05). The total effective rates of common type, nephrotic type and hypertensive type were 90%, 82% and 70%,respectively. Yi-shen-bao had no marked adverse reaction.
Keywords:Yi-shen-bao  Chinese herbal drugs  nephritis  proteinuria
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