Triterpene saponins from Gynostemma cardiospermum |
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Authors: | Yin Feng Zhang Yinan Yang Zhengyi Cheng Qiuqun Hu Lihong |
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Affiliation: | Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China. |
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Abstract: | Six new dammarane glycosides (1-6) and four known compounds, rutin, kaempferol, quercetin, and linalool 3-O-beta-D-glucopyranoside, were isolated from an ethanol extract of the aerial parts of Gynostemma cardiospermum. The structures of 1-6 were elucidated by 1D and 2D NMR spectroscopic interpretation as well as by chemical degradation. Triterpene aglycons containing carbonyl groups at both C-21 and C-28, as found in compounds 1-5, are being reported in the family Cucurbitaceae for the first time. |
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