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Postnatal outcome and placental blood flow after plasmapheresis during pregnancy |
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| Authors: | Mária Jakó Andrea Surányi Márta Janáky Péter Klivényi László Kaizer László Vécsei |
| Affiliation: | 1. Department of Obstetrics and Gynecology, University of Szeged, Szeged, Hungary;2. !["ORCID]("/templates/jsp/images/orcid.png" "\"ORCID") http://orcid/org/0000-0002-3471-0428;3. http://orcid/org/0000-0002-1168-7261;4. Department of Ophthalmology, University of Szeged, Szeged, Hungary;5. Department of Neurology, University of Szeged, Szeged, Hungary;6. Department of Pathology, University of Szeged, Szeged, Hungary |
| Abstract: | Purpose: Plasmapheresis in pregnancy adversely affects maternal hemodynamics, however there are studies suggesting it to reduce pregnancy loss in immunological diseases when medication is more harmful to the fetus. The overall optimal plasmapheresis treatment protocol remains unknown. Materials and methods: A pregnant with neuromyelitis optica was followed up after receiving six volumes of fresh frozen plasma via plasmapheresis. Results: The placenta compensated the hemodynamic change until the 33rd week of gestation, resulting a small for gestational age, otherwise healthy girl. Conclusions: More research is needed on plasma exchange during pregnancy because in our observation placental circulation can adapt to the change in blood pressure. |
| Keywords: | Plasmapheresis placental vascularization intrauterine growth restriction neuromyelitis optica |