| 葡萄糖酸依诺沙星注射液与利巴韦林注射液配伍稳定性的研究 |
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| 引用本文： | 麦曦,刘超.葡萄糖酸依诺沙星注射液与利巴韦林注射液配伍稳定性的研究[J].中国现代应用药学,2007,24(5):414-415. |
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| 作者姓名： | 麦曦 刘超 |
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| 作者单位： | 南昌大学医学院药学系,南昌,330006 |
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| 摘 要： | 目的研究葡萄糖酸依诺沙星注射液与利巴韦林注射液的配伍稳定性。方法考察溶液配伍前后的颜色、pH值、不溶性微粒等变化情况,并用UV和HPLC分别考察配伍前后葡萄糖酸依诺沙星和利巴韦林的含量变化。结果葡萄糖酸依诺沙星注射液与利巴韦林注射液配伍,6 h内溶液颜色基本无变化、pH值、不溶性微粒及含量无明显变化。结论两药配伍后的理化性质稳定,在6h内可以配伍使用。
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| 关 键 词： | 葡萄糖酸依诺沙星 利巴韦林 配伍 稳定性 紫外分光光度法 高效液相色谱 |
| 文章编号： | 1007-7693（2007）05-0414-02 |
| 修稿时间： | 2006-06-07 |
Study on Compatible Stability of Enoxacin Gluconate Injection with Ribavirin Injection |
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| MAI Xi,LIU Chao.Study on Compatible Stability of Enoxacin Gluconate Injection with Ribavirin Injection[J].The Chinese Journal of Modern Applied Pharmacy,2007,24(5):414-415. |
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| Authors: | MAI Xi LIU Chao |
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| Institution: | Pharmaceutical Department of Medical College,Nanchang University,Nanchang 330006,China |
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| Abstract: | OBJECTIVE To study the compatible stability of enoxacin gluconate injection with ribavirin injection.METHODS The changes in color of solution,pH value,insoluble particulates after matching were observed,the contents of enoxacin gluconate and ribavirin were determined by UV,HPLC. RESULTS The color of solution,pH value,insoluble particulates,content didn't change obviously after mixing enoxacin gluconate injection with ribavirin injection in 6 h.CONCLUSION The physical and chemical characters are stable.Enoxacin gluconate injection can mix with ribavirin injection in 6 h. |
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| Keywords: | enoxacin gluconate ribavirin compatible stability UV HPLC |
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