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Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers
Authors:Morana Vojnic  Daisuke Kubota  Christopher Kurzatkowski  Michael Offin  Ken Suzawa  Ryma Benayed  Adam J. Schoenfeld  Andrew J. Plodkowski  John T. Poirier  Charles M. Rudin  Mark G. Kris  Neal X. Rosen  Helena A. Yu  Gregory J. Riely  Maria E. Arcila  Romel Somwar  Marc Ladanyi
Affiliation:1. Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York;2. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;3. Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;4. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York;5. Weill Cornell Medical College, New York, New York;6. Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York
Abstract:
Keywords:Lung adenocarcinoma  Acquired resistance  Osimertinib  CRISPR-Cas9
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