| 高强度聚焦超声治疗兔乳腺移植瘤后残留肿瘤对机体的影响 |
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| 引用本文： | 邹文兵,牛陵川,向理科,朱辉,王智彪.高强度聚焦超声治疗兔乳腺移植瘤后残留肿瘤对机体的影响[J].中国介入影像与治疗学,2010,7(3):309-312. |
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| 作者姓名： | 邹文兵 牛陵川 向理科 朱辉 王智彪 |
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| 作者单位： | 1. 重庆医科大学生物医学工程系,超声医学工程重庆市市级重点实验室,重庆市生物医学工程学重点实验室,重庆,400016
2. 重庆医科大学基础医学院病理学教研室,重庆,40016 |
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| 基金项目： | 教育部新世纪优秀人才支持计划(NCET-05-0775) |
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| 摘 要： | 目的观察高强度聚焦超声（HIFU）治疗兔乳腺移植瘤后残留肿瘤对机体的作用。方法将33只实验兔分为HIFU组、手术组和对照组,分别用HIFU消融和手术切除的方法建立兔乳腺移植瘤治疗后肿瘤残留模型,病理检查确认消融效果。治疗后观察存活时间及肿瘤转移情况。结果HIFU组平均存活时间、8周存活率、腋淋巴结转移时间均长于手术组和对照组（P〈0.05）,手术组、对照组比较差异无统计学意义（P〉0.05）。结论HIFU治疗肿瘤后能有效抑制残留肿瘤的生长和转移,延长荷瘤兔生存时间。
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| 关 键 词： | 高强度聚焦超声消融 乳腺肿瘤 治疗 肿瘤转移 |
| 收稿时间： | 2009/10/29 0:00:00 |
| 修稿时间： | 2009/12/30 0:00:00 |
Effects on body of remnant tumor after implanted rabbit breast tumor treated with high intensity focused ultrasound |
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| ZOU Wen-bing,NIU Ling-chuan,XIANG Li-ke,ZHU Hui and WANG Zhi-biao.Effects on body of remnant tumor after implanted rabbit breast tumor treated with high intensity focused ultrasound[J].Chinese Journal of Interventional Imaging and Therapy,2010,7(3):309-312. |
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| Authors: | ZOU Wen-bing NIU Ling-chuan XIANG Li-ke ZHU Hui and WANG Zhi-biao |
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| Institution: | 1.Department of Biomedical Engineering/a>;Chongqing Medical University/a>;Chongqing Key Laboratory of Ultrasound Medical Engineering/a>;Chongqing Key Laboratory of Biomedical Engineering/a>;Chongqing 400016/a>;China/a>;2.Department of Pathology/a>;School of Basic Medical Sciences/a>;China |
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| Abstract: | Objective To investigate the effect of remnant tumor implanted into rabbit breast tumor after treatment with high intensity focused ultrasound(HIFU) on rabbits.Methods All 33 rabbits were divided into HIFU group,surgery group and control group.The remnant tumor models of implanted rabbit breast tumor were treated with HIFU ablation and surgery,respectively.The effect of treatment was confirmed pathologically.The survival time,survival rate after 8 weeks,the remnant tumor's growth and metastasis in all group... |
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| Keywords: | High-intensity focused ultrasound ablation Breast neoplasms Therapy Neoplasm metastasis |
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