| 超声斑点抑制成像检出乳腺癌微钙化 |
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| 引用本文： | 张文华,崔岚,夏稻子,张宇虹,林萍,高林.超声斑点抑制成像检出乳腺癌微钙化[J].中国医学影像技术,2010,26(12):2306-2308. |
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| 作者姓名： | 张文华 崔岚 夏稻子 张宇虹 林萍 高林 |
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| 作者单位： | 1. 大连医科大学附属第二医院超声科,辽宁,大连,116027
2. 大连医科大学附属第二医院普外科,辽宁,大连,116027 |
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| 基金项目： | 辽宁省教育厅一般项目(20060214)。 |
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| 摘 要： | 目的 探讨超声斑点抑制成像(SRI)在乳腺癌微钙化检出中的应用价值。方法 经手术病理证实的乳腺癌患者92例,术前均接受高频超声和SRI检查。首先行常规高频超声检查,观察乳腺病变的大小、形态、边界、回声、有无微钙化(直径<1 mm)、血流信号以及腋窝淋巴结有无转移;然后加行SRI,观察肿瘤内、外有无微钙化,并分析不同大小、不同病理类型的乳腺肿瘤内存在微钙化情况。结果 92例乳腺癌患者,术前SRI发现42例存在微钙化,其中6例常规高频超声不能确定是否存在微钙化,应用SRI则显示清晰。直径>1.0 cm且≤2.0 cm的肿瘤微钙化的检出率最高(25/35,71.43%),直径>2.0 cm的肿瘤微钙化的检出率最低(17/54,31.48%),二者差异有统计学意义(P<0.05)。术后病理证实导管内原位癌3例,存在微钙化者1例;导管内癌11例,存在微钙化者4例;浸润性导管癌64例,存在微钙化者36例;浸润性小叶癌14例,未见微钙化。结论 乳腺癌中大部分存在微钙化,其病理类型主要为浸润性导管癌和导管内癌。应用超声SRI技术可提高乳腺肿瘤微钙化检出率。
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| 关 键 词： | 超声检查 斑点抑制成像 乳腺肿瘤 微钙化 |
| 收稿时间： | 2010/7/31 0:00:00 |
| 修稿时间： | 2010/8/24 0:00:00 |
Detection of microcalcification in breast cancer with ultrasound speckle reduction imaging |
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| ZHANG Wen-hu,CUI Lan,XIA Dao-zi,ZHANG Yu-hong,LIN Ping and GAO Lin.Detection of microcalcification in breast cancer with ultrasound speckle reduction imaging[J].Chinese Journal of Medical Imaging Technology,2010,26(12):2306-2308. |
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| Authors: | ZHANG Wen-hu CUI Lan XIA Dao-zi ZHANG Yu-hong LIN Ping and GAO Lin |
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| Institution: | Department of Ultrasound, the Second Affiliated Hospital ofDalian Medical University, Dalian 116027, China;Department of Surgery, the Second Affiliated Hospital ofDalian Medical University, Dalian 116027, China;Department of Ultrasound, the Second Affiliated Hospital ofDalian Medical University, Dalian 116027, China;Department of Ultrasound, the Second Affiliated Hospital ofDalian Medical University, Dalian 116027, China;Department of Ultrasound, the Second Affiliated Hospital ofDalian Medical University, Dalian 116027, China;Department of Ultrasound, the Second Affiliated Hospital ofDalian Medical University, Dalian 116027, China |
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| Abstract: | Objective To assess the value of ultrasound speckle reduction imaging (SRI) in detection of microcalcification in breast cancer. Methods Ninety-two patients with breast cancer confirmed with pathology underwent high frequency ultrasound and SRI before operation. High frequency ultrasound was performed to observe the size, shape, boundary, microcalcifications (diameter <1 mm), blood flow signal and the metastasis of axillary nodes. Then SRI was performed to detect the microcalcifications again. Microcalcifications in tumors with different size and different pothologic types were analyzed. Results Preoperative high frequency ultrasound detected microcalcifications in 36 of 92 patients, and SRI found microcalifications in 42 patients clearly. The detection rate of microcalcifications was relatively high in tumors with diameter greater than 1.0 cm and no more than 2.0 cm (25/35, 71.43%), but only 31.48% (17/54) in tumors with diameter greater than 2.0 cm. Pathology confirmed that 1 of 3 patients with ductal cacinoma in situ, 4 of 11 intraductal cacinoma patients, 36 of 64 patients with infitrating ductal carcinoma had microcalcifications. No microcalification was found in 14 patients with infitrating lobular cacinoma. Conclusion Most of breast cancer patients have microcalifications, while the pathologic types are mainly infitrating ductal carcinoma and ductal cacinoma. SRI can detect more microcalifications in breast mass than high frequency ultrasound. |
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| Keywords: | Ultrasonography Speckle reduction imaging Breast neoplasms Microcalcification |
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