| 远志50%醇提取物微乳制备工艺的研究 |
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| 引用本文： | 吕敏,;张春龙,;周保腾.远志50%醇提取物微乳制备工艺的研究[J].山西中医学院学报,2014(5):27-29. |
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| 作者姓名： | 吕敏 ;张春龙 ;周保腾 |
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| 作者单位： | [1]山西中医学院第三中医院,山西太原030006; [2]山西中医学院,山西太原030024 |
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| 基金项目： | 山西省科技攻关项目（20100311090） |
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| 摘 要： | 目的:研究远志50%醇提取物微乳的制备工艺。方法:考察远志醇提物在不同表面活性剂、助表面活性剂和油相中的溶解度,通过伪三元相图的绘制、微乳粒径的测定和稳定性的考察,确定微乳最佳处方。结果:微乳最佳处方比例为聚山梨酯-80∶无水乙醇∶油酸乙酯∶蒸馏水∶远志50%醇提取物=27∶18∶5∶100∶2.8。结论:该工艺制备的远志50%醇提物微乳粒径小,稳定性好。
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| 关 键 词： | 远志 50%醇提取物 微乳 伪三元相图 |
Preparation technology of microemulsion of extraction from Polygala tenuifolia Willd with 50% ethanol |
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| Institution: | Lv Min, Zhang Chunlong, Zhou Baoteng (1.The Third Hospital Affiliated to Shanxi College of TCM, Taiyuan Shanxi 030006;2.Shanxi College of TCM, Taiyucm Shanxi 030024) |
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| Abstract: | Objective：To study preparation technology of microemulsion of extraction from Polygala tenuifolia Willd with 50% ethanol. Methods：The equilibrium solubility of extraction from Polygala tenuifolia Willd with ethanol （EPTWE） in different compositions of suffaetant, cosuffactant and oil phase was observed. The microemulsion formulation was optimized based on obtained pseudo-ternary phase diagrams,particle size and the stability of microemulsion. Results ：The optimal microemulsion formulation was composed of Tween-80,Ethyl alcohol,Ethyl Oleate,water and EPTWE. The ratio of them was 27：18：5： lO0：2.8.Conclusion ：The acquired microemulsion with small particle size is table. |
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| Keywords: | Polygala tenuifolia Willd extraction with 50% ethanol microemulsion pseudo-ternary phase diagram |
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