| 富血小板纤维蛋白修复牙种植体周围骨缺损的研究 |
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| 引用本文： | 杨全全,何家才,杨瑞,陈镇,方冬冬.富血小板纤维蛋白修复牙种植体周围骨缺损的研究[J].安徽医科大学学报,2012,47(5):581-584. |
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| 作者姓名： | 杨全全 何家才 杨瑞 陈镇 方冬冬 |
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| 作者单位： | 安徽医科大学附属口腔医院颌面外科,合肥,230032;安徽医科大学第二附属医院口腔科,合肥,230601 |
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| 基金项目： | 安徽高校省级自然科学研究重点项目,安徽省自然科学基金项目,安徽医科大学博士科研资助基金 |
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| 摘 要： | 采用牙种植术将36颗牙种植体植于6只杂种犬双侧下颌缺牙区,同时在种植体近中造3.5 mm×3.5 mm×3.5mm的骨缺损,然后填入β-TCP/PRF混合物、β-TCP,另设空白对照组(不做任何处理)于各骨缺损区,分别于种植术后4、8、12周各处死2只犬,行大体、X线及组织学观察各个时期各组骨缺损区的成骨情况。植入的36颗种植体无脱落,无明显不良并发症发生。β-TCP/PRF混合物是一种良好的骨修复材料,具有促进新骨形成的作用,有利于骨组织的愈合。
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| 关 键 词： | 富血小板纤维蛋白 β相磷酸三钙 种植牙 骨缺损 |
Study on restoration of bone defects around dental implants by platelet-rich fibrin |
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| Institution: | Yang Quanquan,He Jiacai,Yang Rui,et al(College of Stomatology,Anhui Medical University,Hefei 230032) |
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| Abstract: | 36 dental implants were separately implanted in each side of the mandibule of 6 dogs.At the same time,a 3.5 mm×3.5 mm×3.5 mm size bone defect was created in the mesial aspect of each implant.3 kinds of substitutes were grafted in the bone defects:β-TCP/PRF compounds,β-TCP and blank control(do not make any deal).Every 2 dogs were sacrificed at 4,8 and 12 weeks after the implantation,and gross observation,X-rays and histopathology were examined.The results showed 36 dental implants did not fall off,and no severe complications occurred.So β-TCP/PRF is a better bone repair material with the promotion of new bone formation and the elevation of healing quality. |
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| Keywords: | platelet-rich fibrin β-tricalcium phosphate dental implant bone defect |
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