| 血浆同型半胱氨酸水平与缺血性脑卒中复发的关系 |
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| 引用本文： | 陆敏,姜建东,袁存国,王军,赵艳霞. 血浆同型半胱氨酸水平与缺血性脑卒中复发的关系[J]. 临床神经病学杂志, 2009, 22(2) |
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| 作者姓名： | 陆敏 姜建东 袁存国 王军 赵艳霞 |
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| 作者单位： | 南京医科大学附属南京第一医院神经内科,210006;南京医科大学附属南京第一医院神经内科,210006;南京医科大学附属南京第一医院神经内科,210006;南京医科大学附属南京第一医院神经内科,210006;南京医科大学附属南京第一医院神经内科,210006 |
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| 摘 要： | 目的探讨血浆同型半胱氨酸(Hcy)水平与缺血性脑卒中(ICS)复发的关系。方法用荧光偏振免疫法检测303例初发、97例复发ICS患者[动脉粥样硬化性血栓性脑梗死173例(血栓组)、腔隙性脑梗死170例(腔梗组)、心源性脑栓塞57例(栓塞组)]及200例非脑血管病患者(对照组)的血浆Hcy水平。对ICS复发因素进行多因素回归分析。结果(1)ICS患者血浆Hcy水平[血栓组(16.17±10.83)μmol/L、腔梗组(14.64±7.71)μmol/L、栓塞组(15.75±6.8)μmol/L]显著高于对照组[(9.61±4.22)μmol/L](均P<0.01);各类型ICS组之间血浆Hcy水平差异无统计学意义(均P>0.05);(2)ICS复发患者血浆Hcy水平[(18.04±10.68)μumol/L]显著高于初发患者[(14.57±8.50)μmol/L](P<0.01),以及高Hcy血症比率(50.5%)显著高于初发患者(32.3%)(P<0.01);(3)各类型ICS复发患者之间血浆Hcy水平差异无统计学意义(均P>0.05);(4)高Hcy血症、糖尿病是ICS复发的独立危险因素(P<0.001,P...
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| 关 键 词： | 缺血性脑卒中 脑梗死 同型半胱氨酸 复发 危险因素 |
Relationship between plasma homocysteinemia concentration and recurrence of ischemical cerebral stroke |
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| LU Min,JIANG Jian-dong,YUAN Cun-guo,et al.. Relationship between plasma homocysteinemia concentration and recurrence of ischemical cerebral stroke[J]. Journal of Clinical Neurology, 2009, 22(2) |
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| Authors: | LU Min JIANG Jian-dong YUAN Cun-guo et al. |
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| Affiliation: | LU Min,JIANG Jian-dong,YUAN Cun-guo,et al.Department of Neurology,Nanjing First Hospital Affiliated to Nanjing Medical University,Nanjing 210006,China |
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| Abstract: | Objective To investigate the relationship between concentration of plasma homocysteine(Hcy) and recurrence of ischemical cerebral stroke(ICS).Methods Plasma Hcy concentration were measured using fluorescence polarization immunoassay(FPLA) in 303 primary and 97 recurrent ICS patients [173 cases of atherosclerotic thrombotic cerebral infarction(thrombotic group),170 cases of lacunar cerebral infarction(lacunar group) and 57 cases of cardiogenic embolism] and 200 non-cerebrovascular disease patients(control gr... |
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| Keywords: | ischemical cerebral stroke cerebral infarction homocysteine recurrent risk factor |
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