Analgesic activity of Cassia alata leaf extract and kaempferol 3-o-sophoroside |
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| Authors: | S Palanichamy S Nagarajan |
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| Affiliation: | Department of Pharmacology, Thanjavur Medical College, India. |
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| Abstract: | The analgesic activity of an extract of the leaves of Cassia alata and kaempferol 3-O-sophoroside were studied after intraperitoneal injection in mice and rats using the tail clip, tail flick, tail immersion and acetic acid-induced writhing methods and the results compared with morphine. Maximum analgesic activity of the extract was apparent 120 min after injection. Fifty milligrams of kaempferol 3-O-sophoroside appeared equivalent to 100 mg of the extract. |
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