海南地区不同性别非瓣膜病心房纤颤的临床特点

目的了解海南地区不同性别非瓣膜病心房纤颤（NVAF）患者的病因，临床伴随疾病以及脑卒中发生的高危因素。方法将随机纳入的329名海南NVAF患者按男女性别进行队列分析。结果NVAF男、女两组的首要病因均为冠心病，次要病因在女性组为甲状腺机能亢进性心脏病（17．39％）；在男性组为高血压性心脏病（10．75％）。两组NVAF患者脑卒中的发病率十分接近，但伴随疾病各有特点。脑卒中发生的独立危险因素在女性NVAF为高血压（P=0．003）和未抗栓治疗（P=0．028），在男性NVAF为高血压（P=0．004）、未抗栓治疗（P-=0.049）和年龄（P-0．004）。结论海南地区女性和男性NVAF患者各自具有其动脉粥样硬化基础及发生脑卒中等血栓栓塞事件的临床伴随疾病特点。

The clinical characteristics of nonvalvular atrial fibrillation in patients of Hainan with different gender

Objective To investigate risk factors of stroke, the etiology and clinical characteristics of non-valvular atrial fibrillation （NVAF） patients in different gender. Methods Cohort study of 329 NVAF patients in Hainan Province were randomly enrolled. Results Top etiology in both male and female groups was coronary heart disease. The secondary etiology was hyperthyroidism heart disease in female group （17.39%）; hypertensive heart disease in male group （10.75%）. Even though these two groups had similar incidence of stroke, they had their own clinical characteristics. Independent risk factors of stroke in female group were hypertension（P=0.003 ）, treatment （P=0.028）while in male group were h ypertension（P =0.004） ,treatment（P=0.049）and age（P=0.004）. Conclusions Male and female NVAF patients of Hainan have their own atherosclerosis bases and the tendency to develop thromboembolism.