| 异维A酸红霉素凝胶治疗轻、中度寻常性痤疮临床观察 |
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| 引用本文： | 张国强,王文氢,康瑞花,王曙霞,王正想,高顺强. 异维A酸红霉素凝胶治疗轻、中度寻常性痤疮临床观察[J]. 中国皮肤性病学杂志, 2011, 25(5) |
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| 作者姓名： | 张国强 王文氢 康瑞花 王曙霞 王正想 高顺强 |
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| 作者单位： | 河北医科大学第四医院皮肤科,河北,石家庄,050011 |
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| 摘 要： | 目的观察异维A酸红霉素凝胶治疗轻、中度寻常性痤疮的疗效和安全性。方法采用单盲随机阳性药物对照的临床试验。治疗组采用异维A酸红霉素凝胶,每晚外用1次;对照组采用他扎罗汀乳膏,每晚外用1次,连续应用56天。结果治疗后,两组皮损数目均减少。治疗组和对照组有效率分别为80.56%和65.71%,差异有统计学意义(P<0.05);两组不良反应发生率分别为13.89%和21.34%,差异无统计学意义(P>0.05)。结论异维A酸红霉素凝胶治疗轻、中度寻常性痤疮安全有效,值得临床推广应用。
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| 关 键 词： | 痤疮 寻常性 治疗 异维A酸 红霉素 |
Clinical Application and Efficacy of Isotretinoin Erythromycin Gel for Mild to Moderate Acne Vulgaris |
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| ZHANG Guo-qiang,WANG Wen-qing,KANG Rui-hua,WANG Shu-xia,WANG Zheng-xiang,GAO Shun-qiang. Clinical Application and Efficacy of Isotretinoin Erythromycin Gel for Mild to Moderate Acne Vulgaris[J]. The Chinese Journal of Dermatovenereology, 2011, 25(5) |
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| Authors: | ZHANG Guo-qiang WANG Wen-qing KANG Rui-hua WANG Shu-xia WANG Zheng-xiang GAO Shun-qiang |
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| Affiliation: | ZHANG Guo-qiang,WANG Wen-qing,KANG Rui-hua,WANG Shu-xia,WANG Zheng-xiang,GAO Shun-qiang(Department of Dermatology,the Fourth Affiliated Hospital of Hebei Medical University,Shijiazhuang 050011,China) |
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| Abstract: | Objective To evaluate the efficacy and safety of isotretinoin erythromycin gel in the treatment of mild to moderate acne vulgaris.Methods By a single-blind randomized controlled method,a total of 160 patients with mild to moderate acne vulgaris were assigned to one of the following two groups:the trail group which was treated with isotretinoin erythromycin gel(80 cases),while the control group was treated with tazarotene cream(80 cases).After treatment for 56 consecutive days with each drug respectively sme... |
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| Keywords: | Acne Vulgaris Treatment Isotretinoin Erythromycin |
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