增殖性红斑继发鳞状细胞癌1例

患者男,37岁。龟头红斑、溃烂和渗液半年余。皮肤科情况:龟头包皮系带处可见直径约2.5cm糜烂面,上有少许渗液,皮疹中央可见乳头瘤状增生。皮损组织病理示:鳞状细胞癌(中～高度分化)。诊断:增殖性红斑,鳞状细胞癌。予5%咪喹莫特软膏外用,ALA光动力疗法4次,无好转。予阴茎部分切除术,切除断端组织进行组织病理检查,未见癌细胞,术后切口愈合可。

A Case of Erythroplasia of Queyrat Developing to Squamous Cell Cancer

The case involved a 37-year-old man who had developed a erythematous lesion with effusion of 6 months on his glans penis. On dermatological examination,an area of anabrosis measuring 2.5×2.5cm was observed on the frenulum of prepuce,with a little effusion and slightly hyperplasia on it. The skin biopsy from specimen revealed squamous cell cancer (moderately to well-differentiated),which was consistent with Erythroplasia of Queyrat,Squamous cell cancer. Imiquimod 5% cream and ALA-PDT were used to the lesion,but it seemed ineffective. At last,the patient recevied the penis partial excision. No cancer cell was found at the broken ends of fractured bone and the wound healed well.