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Melkersson-Rosenthal综合征(附3例报告)
引用本文:李小龙,孙华,刘军,蒲传强.Melkersson-Rosenthal综合征(附3例报告)[J].中国神经免疫学和神经病学杂志,2002,9(1):53-55.
作者姓名:李小龙  孙华  刘军  蒲传强
作者单位:1. 解放军总医院神经内科,北京,100853
2. 山东省龙口矿务局北皂煤矿医院,山东,龙口,265700
摘    要:目的 探讨Melkersson-Rosenthal综合征(MRS)的临床特点及发病机制。方法 分析本院近10年来收治的3例完全型MRS患者临床及随访资料。结果 3例患者临床资料符合完全性MRS的诊断,即间歇性面瘫、再生性唇面肿及皱襞舌,其中1例有家族性皱襞舌。结论 MRS发病机制可能与免疫功能异常所致组织炎性肉芽肿有关,激素治疗有效。

关 键 词:Melkersson-Rosenthal综合征  免疫  炎性肉芽肿  激素
文章编号:1006-2963(2002)01-0053-03
修稿时间:2000年8月1日

Melkersson-Rosenthal Syndrome(3 Cases Report)
LI Xiao long ,SUN Hua ,LIU Jun ,PU Chuan qiang.Melkersson-Rosenthal Syndrome(3 Cases Report)[J].Chinese Journal of Neuroimmunology and Neurology,2002,9(1):53-55.
Authors:LI Xiao long  SUN Hua  LIU Jun  PU Chuan qiang
Institution:LI Xiao long 1,SUN Hua 2,LIU Jun 1,PU Chuan qiang 1
Abstract:Objective To investigate the clinical manifestation of Melkersson Rosenthal syndrome(MRS).Methods We report three definite MRS cases in our hospital from 1991 to 2000 and discuss its causes, pathogenesis and clinical features refering to recent literature.Results MRS is a rare disorder of unknown etiology, with the clinical manifestation of recurrent lip and/or face swelling,fissured tongue,and intermittent peripheral facial palsy.Conclusions MRS can be effectively treated with glucocorticosteroids. This syndrome is hard to be correctly diagnosed in the early stage.It was concluded that immune dysfunction might participate in the pathogenesis of this syndrome, and pathologically was a granuloma.
Keywords:melkersson  Rosenthal syndrome(MRS)  immunohistochemistry  granuloma  glucocorticosteroids
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